Results 161 to 170 of about 124,521 (292)

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

A Later Stone Age quartz knapping workshop and fireplace dated to the Early Holocene in Senegal: The Ravin Blanc X site (RBX). [PDF]

PLoS One
Pruvost C, Huysecom E, Garnier A, Hajdas I, Höhn A, Lespez L, Rasse M, Douze K, Soriano S, Fichet V, Saulnier-Copard S, Ndiaye M, Mayor A.   +12 more
europepmc   +1 more source

THE IMAGE OF THE HISTORY OF ANCIENT CULTURES OF THE STONE AGE OF WESTERN PRIAMURYE

, 2018
Danila Bolotin, Oleg Shelomikhin
openalex   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Climate seasonality and predictability during the middle stone age and implications for technological diversification in early Homo sapiens. [PDF]

Sci Rep
Timbrell L, Clark J, Linares-Matás G, Boisard S, Arous EB, Blinkhorn J, Grove M, Scerri EML.   +7 more
europepmc   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Stone Age Culture of Malwa

Journal of the Palaeontological Society of India, 1957
H. D. Sankalia, A. P. Khatri
doaj   +1 more source

First stage in technological production of Stone Age animal teeth pendants: evidence from Zvejnieki (Latvia) and wider social implications. [PDF]

Archaeol Anthropol Sci
Macāne A, Nordqvist K, Mannermaa K, Needham A, Pomstra D, Alcobendas GC, Reblis J, Zagorska I, Little A.   +8 more
europepmc   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

A holocene n-alkane stable isotope record from Wonderwerk Cave, South Africa and its implications for the later stone age record. [PDF]

Sci Rep
Ecker M, Rhodes S, Andersen N, Horwitz LK, Chazan M, Makarewicz CA.   +5 more
europepmc   +1 more source