Results 151 to 160 of about 12,502 (264)

Declining demand and circular transition possibilities of sand, gravel and crushed stone in China. [PDF]

Nat Commun
Ren Z, Jiang M, Behrens P, Chen D, Mostert C, Zhou W, Li C, Li F, Liu L, Wang H, Xu M, Hertwich E, Bringezu S, Zhu B.   +13 more
europepmc   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Analysis of the Thermal Properties of Soft Silica Limestone Walls of Traditional Buildings in Central Poland. [PDF]

Materials (Basel)
Gorączko A, Szczepaniak P, Gorączko M.
europepmc   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Understanding building damage through the lens of the Swiss post-seismic reconnaissance mission of 2023 Al Haouz, Morocco, earthquake. [PDF]

Sci Rep
Imtiaz A, Saloustros S, Beqiraj M, Cortés G, Devaux M, Lattion E, Zhu Y, Sehaqui H.   +7 more
europepmc   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Fluorine mass balance in commercial stone sealers from the US market and evaluation of PFAS-free alternatives.

Environ Sci Process Impacts
Savvidou EK, Cott S, Desai K, Benskin JP, Ray HL, Young A, Allen JG, Whitehead HD, Peaslee GF, Cousins IT.   +9 more
europepmc   +1 more source

Assessing the influence of building data choice on wildland-urban interface delineation in mainland Portugal. [PDF]

Sci Rep
Barbosa B, Oliveira S, Mário C, Rocha J.   +3 more
europepmc   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Research on the protection and restoration technology of glazed components in ancient architecture. [PDF]

PLoS One
Chen Y, Yu L, Chen L, Ouyang L, Wang N.
europepmc   +1 more source