Results 41 to 50 of about 3,504,534 (351)

Analysis of thermal performance of wood and exposed stone-walled buildings in mountainous areas with building envelop variations

open access: yesJournal of Applied Engineering Science, 2019
A building’s ability in creating thermal convenience will produce energy saving. Such an ability of a building is known as building thermal performance.
H. Hermawan   +3 more
semanticscholar   +1 more source

Understanding and controlling the ingress of driven rain through exposed, solid wall masonry structures [PDF]

open access: yes, 2014
Long term performance of historic buildings can be affected by many environmental factors, some of which become more apparent as the competence of the fabric deteriorates.
Bowler   +5 more
core   +1 more source

The building stones and slates of Killin : an investigation of stone for the built heritage [PDF]

open access: yes, 2010
The village of Killin lies in an area of dramatic landscape and mountain scenery. The use of local stone in the buildings gives a direct connection to this landscape and reflects the local geology, comprising mostly metamorphic rocks of Precambrian age
Albornoz-Parra, L.J.   +5 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

An investigation into the non-uniform decay of Hardwick Stone [PDF]

open access: yes, 2009
Hardwick stone as used on the vernacular Hardwick Estate buildings decays in a non-uniform way. Typically stones at Hardwick decay cavernously leaving the mortar matrix behind.
Brough, Robert, Laycock, Elizabeth
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Building in Historical Areas: Identity Values and Energy Performance of Innovative Massive Stone Envelopes with Reference to Traditional Building Solutions [PDF]

open access: yes, 2018
The intrinsic nature of local rocks shaped the features of built heritage in historical centers. The resulting building culture is part of the cultural heritage itself, and must be considered when building in such areas, while it is essential to solve ...
Ferrero, Marco   +2 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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