Results 41 to 50 of about 465,615 (309)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
TiO2-SiO2 Coatings with a Low Content of AuNPs for Producing Self-Cleaning Building Materials
The high pollution levels in our cities are producing a significant increase of dust on buildings. An application of photoactive coatings on building materials can produce buildings with self-cleaning surfaces.
Manuel Luna +3 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Studies of Oxford Stone as a Contribution to Environmental Geomorphology
Much scientific research has been conducted on Oxford stone, of which the historical buildings of central Oxford, UK are comprised. This paper reviews all published literature to-date specifically for Oxford stone, compiling an inventory of studies.
Thornbush Mary J.
doaj +1 more source
Derivation of fragility curves for traditional timber-framed masonry buildings using nonlinear static analysis [PDF]
Recent earthquakes and two experimental campaigns on timber-framed masonry walls have shown that timber-framed masonry buildings possess a good displacement capacity and hence can withstand severe earthquakes without collapse.
Kappos, A. J., Kouris, L.A.S.
core
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Frost damage and restoration of limestone domes and spheres in a heritage building [PDF]
B
Van Bogaert, Philippe
core +2 more sources
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Green Maintenance for Heritage Buildings: Low Carbon Repair Appraisal Approach on Laterite Stones
Sustainability is commonly encapsulated economic, environmental and societal domains. Low carbon repair for heritage buildings also conforms to these broad domains, without exception.
B.A. Kayan, I.A. Halim, N.S. Mahmud
doaj +1 more source
Objective The great demand for urban landscape improvement and reconstruction has required increasing dredging practices for waterfront buildings, particularly antique buildings. To effectively protect such antique buildings, the influence of dredging on
Yipeng Li +3 more
doaj +1 more source

