Results 211 to 220 of about 190,915 (301)

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Multi-target litholytic strategy toward calcium oxalate stone therapy: a fundamental study. [PDF]

Front Pharmacol
Xia S, Shen K, Yang H, Li Y, Mu W, Shen J.   +5 more
europepmc   +1 more source

Mechanically Adaptive Polyimide Interfaces for Stable High‐Voltage NCM–Sulfide All‐Solid‐State Batteries

Advanced Science, EarlyView.
A mechanically adaptive polyimide interface dynamically stabilizes single‐crystal cathodes in sulfide all‐solid‐state batteries. By integrating robust chemical coordination with viscoelastic compliance, this smart coating suppresses parasitic reactions and accommodates cyclic volume expansion.
Jiatao Wu, Wenjin Li, Rui Wang, Peng Wang, Kaiyuan Deng, Chengshuai Chang, Chuan Xie, Lei Yao, Guangliang Gary Liu   +8 more
wiley   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Editorial: Urinary lithiasis in children

Frontiers in Pediatrics
Alberto Parente, Rubén Ortiz, Sonia Pérez-Bertólez, Francisco Javier Reed   +3 more
doaj   +1 more source

Bacteriological Analysis of Urine Cultures and Related Clinical Features in Patients with Infection Stones: A Single-Center Retrospective Cohort Analysis from Beijing, China. [PDF]

Infect Drug Resist
Ding X, Chi Z, Li J, Chen G, Ji C, Hu W.
europepmc   +1 more source

Large‐Scale Growth of Self‐Poled Ferroelectric Rashba Semiconductor α‐GeTe(111) Thin Films: A Crucial Step Towards Future CMOS‐Compatible Ferroelectric Spintronic Devices

Advanced Science, EarlyView.
Ferroelectric Rashba semiconductors promise ultralow‐power devices but lack industry‐quality films. This work demonstrates CMOS‐compatible fabrication of high‐quality α‐GeTe(111) films via magnetron sputtering, enabled by a 5 nm Sb2Te3 seed layer. Structural and ferroelectric analyses show robust, switchable polarization comparable to MBE films, paving
Jules Lagrave, Nicolas Bernier, Thomas Jalabert, Yoann Brûlé, Damien Térébénec, Pierre Meilleur, Hervé Roussel, Jean‐Baptiste Dory, Oussama J. Mouawad, Thibault Chommaux, Cristian Mocuta, Dominique Thiaudière, Laurent Vila, Françoise Hippert, Pierre Noé   +14 more
wiley   +1 more source

Gallbladder perforation during peroral holmium laser lithotripsy. [PDF]

Endoscopy
Zhu R, Long H, Zhu Y, Zhao Q, Wang H, Wang F.   +5 more
europepmc   +1 more source

Outstanding TC Enhancement in 5d–3d Y2NiIrO6 by Compression

Advanced Science, EarlyView.
Double perovskite Y2NiIrO6 with half filed 3d eg–5d t2g configuration, exhibits first experimental example of pressure‐enhanced magnetic interaction in iridate and iridate‐related systems. Its Curie temperature increase from 192 to 243 K at 17 GPa. Herein, the orthogonal eg–t2g pathway remains robust even under compression‐induced lattice distortion ...
Zheng Deng, Yao Zhang, Sijia Zhang, Jing Song, Wanli He, Yuanzhe Li, Meilin Jin, Xiang Li, Guanghua Liu, Zhen Dong, Jingkai Bi, Wenmin Li, Jianfa Zhao, Jun Zhang, Yi Peng, Luchuan Shi, Junling Meng, Xiancheng Wang, Changqing Jin   +18 more
wiley   +1 more source