Results 131 to 140 of about 679,191 (389)

Syntonets: Toward A Harmony-Inspired General Model of Complex Networks [PDF]

open access: yes, 2019
We report an approach to obtaining complex networks with diverse topology, here called syntonets, taking into account the consonances and dissonances between notes as defined by scale temperaments. Though the fundamental frequency is usually considered, in real-world sounds several additional frequencies (partials) accompany the respective fundamental,
arxiv   +1 more source

Phonological Development in the Early Speech of an Indonesian-German Bilingual Child [PDF]

open access: yes, 2016
Current research in bilingual children’s language development with one language dominant has shown that one linguistic system can affect the other. This is called Crosslinguistic Influence (CLI).
Bosch   +51 more
core   +1 more source

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch   +11 more
wiley   +1 more source

CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti‐tumoral compounds

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1092-1116, April 2025.
FOXL2 c.402C>G mutation drives granulosa cell tumors. Using CRISPR technology, we selectively corrected this mutation, reducing malignancy and increasing sensitivity to dasatinib and ketoconazole. Transcriptomic changes revealed potential therapeutic targets, demonstrating CRISPR's promise for treating this rare ovarian cancer.
Sandra Amarilla‐Quintana   +17 more
wiley   +1 more source

A Generative Study of Phoneme System of Sarhaddi Balochi Dialect of Granchin [PDF]

open access: yesمطالعات زبان‌‌ها و گویش‌های غرب ایران, 2014
Generative linguists are specifically interested in phonology as an important part of the grammar of any language. Generative phonology the beginning of which can be attributed to Chomsky and Halle (1968), has been proposed in terms of specific patterns ...
Abbas Ali Ahangar   +3 more
doaj  

Turkish /h/ deletion : evidence for the interplay of speech perception and phonology [PDF]

open access: yes, 2013
It has been hypothesized that sounds which are less perceptible are more likely to be altered than more salient sounds, the rationale being that the loss of information resulting from a change in a sound which is difficult to perceive is not as great as ...
Mielke, Jeff
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

A non-invasive device to measure mechanical interaction between tongue, palate and teeth during speech production [PDF]

open access: yesProceedings of the 4th International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications, MAVEBA'2005 Firenze University Press (Ed.) (2005) 1-4, 2006
This paper describes an original experimental procedure to measure the mechanical interaction between the tongue and teeth and palate during speech production. It consists in using edentulous people as subjects and to insert pressure sensors in the structure of their complete dental prosthesis.
arxiv  

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