Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee+5 more
wiley +1 more source
Identification of stop consonant voicing and place of articulation by listeners with normal hearing and by listeners with mild, moderate, severe, and profound hearing impairments [PDF]
Deborah Johnson+3 more
openalex +1 more source
Variable finals in proto-Sino-Tibetan [PDF]
This paper concentrates on variable finals, and argues that just as we find a certain amount of both rule-governed and non-rule governed variation in modern languages, in reconstructing Proto-Sino-Tibetan we should recognize the possibility of these ...
LaPolla, Randy J.
core
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source
Vowel constriction effects on the perception of F 1 offset and vowel duration cues for word final stop consonant voicing [PDF]
Rebecca M. Fischer, Ralph N. Ohde
openalex +1 more source
Consonant Context Effects on Vowel Sensorimotor Adaptation [PDF]
Speech sensorimotor adaptation is the short-term learning of modified articulator movements evoked through sensory-feedback perturbations. A common experimental method manipulates acoustic parameters, such as formant frequencies, using real time ...
Bernal, Brittany A.+4 more
core +1 more source
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu+6 more
wiley +1 more source
Investigating Causal Cues: Strengthening Spoofed Audio Detection with Human-Discernible Linguistic Features [PDF]
Several types of spoofed audio, such as mimicry, replay attacks, and deepfakes, have created societal challenges to information integrity. Recently, researchers have worked with sociolinguistics experts to label spoofed audio samples with Expert Defined Linguistic Features (EDLFs) that can be discerned by the human ear: pitch, pause, word-initial and ...
arxiv
Perception of stop consonant formant transitions by normal and high-frequency sensorineurally hearing-impaired listeners: Identification and psychoacoustic evidence [PDF]
T. Ochs, Larry E. Humes, Ralph N. Ohde
openalex +1 more source