Results 321 to 330 of about 679,191 (389)

Spatiotemporal Control Over Protein Release from Artificial Cells via a Light‐Activatable Protease

Advanced Biology, Volume 9, Issue 5, May 2025.
Stimulus‐responsive protein release is essential for intercellular communication. Mimicking this functionality in artificial cells is promising to study the working principles of cellular signaling. Herein, an engineered light‐activatable protease is implemented in a coacervate‐based artificial cell platform to establish user‐defined spatiotemporal ...
Arjan Hazegh Nikroo, Wiggert J. Altenburg, Thijs W. van Veldhuisen, Luc Brunsveld, Jan C. M. van Hest   +4 more
wiley   +1 more source

Building a benchmark dataset for the Kurdish news question answering. [PDF]

Data Brief
Saeed AM.
europepmc   +1 more source

Depletion of TP53 in Human Pluripotent Stem Cells Triggers Malignant‐Like Behavior

Advanced Biology, Volume 9, Issue 4, April 2025.
Human pluripotent stem cells (hPSCs) with TP53‐depleting mutations are generated, mimicking commonly occurring events in vitro. Loss of TP53 does not alter pluripotency status or in vitro differentiation potential but causes genetic instability and transcriptome changes and confers superior clonal and anchorage‐free growth and higher chemotherapeutic ...
Joaquin Montilla‐Rojo, Thomas F. Eleveld, Marnix van Soest, Sanne Hillenius, Dennis M. Timmerman, Ad J. M. Gillis, Bernard A. J. Roelen, Christine L. Mummery, Leendert H. J. Looijenga, Daniela C. F. Salvatori   +9 more
wiley   +1 more source

Speech and language biomarkers for Parkinson's disease prediction, early diagnosis and progression. [PDF]

NPJ Parkinsons Dis
Cao F, Vogel AP, Gharahkhani P, Renteria ME.   +3 more
europepmc   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Multitaper Spectrum Analysis of Consonants Produced by Patients With Dentofacial Disharmonies. [PDF]

J Speech Lang Hear Res
Tran A, Oakley M, Paye C, Trudan E, Ghaltakhchyan N, Turvey T, Blakey G, Zajac D, Mielke J, Jacox LA.   +9 more
europepmc   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

The Effects of Home Language Use on Spanish Speech Measures in Bilingual Children With Hearing Loss Who Use Cochlear Implants and Their Peers With Normal Hearing. [PDF]

J Speech Lang Hear Res
Hein Machado S, Sweeney A, Hernandez AE, Bunta F.   +3 more
europepmc   +1 more source

Redundant voicing and register in Mnong Râlâm. [PDF]

Phonetica
Brunelle M, Đinh LG, Tạ TT.
europepmc   +1 more source

Family Medicine in Times of War. [PDF]

Ann Fam Med
Borkan JM.
europepmc   +1 more source