Results 61 to 70 of about 4,341 (303)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
On the Lenis Stop Consonants in Korean [PDF]
, 2000 This paper explores the acoustic cues for differentiating the lenis stop consonants from the other two stop categories in Korean- i.e .. the tense and aspirated stop consonants. For this goal.
Ahn, Hyunkee
core
A Generative Study of Phoneme System of Sarhaddi Balochi Dialect of Granchin [PDF]
مطالعات زبانها و گویشهای غرب ایران, 2014 Generative linguists are specifically interested in phonology as an important part of the grammar of any language. Generative phonology the beginning of which can be attributed to Chomsky and Halle (1968), has been proposed in terms of specific patterns ...
Abbas Ali Ahangar +3 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Formation of Stop Consonants in Germanic and Slavic Languages [PDF]
, 2015 У статті деталізовано становлення зімкнених приголосних в індоєвропейській мовній системі, їх розвиток у спільногерманській та давньослов’янській мовах за допомогою діахронічних констант.
Rudkivskyy, O. P. +1 more
core
Automatic discrimination of Polish stop consonants based on bursts analysis
Archives of Acoustics, 2014 The aim of the work reported is to test the possibility of speaker- and context-independent automatic discrimination of Polish stop consonants.
P. DOMAGAŁA, L. RICHTER
doaj
Investigating the Effect of Speech Rate on the Start Time of the Voicing of Persian Plosives of Persian Standard in Continuous Speech [PDF]
̒Ilm-i Zabān, 2019 This study investigated the effect of speaking rate on the voice onset time (vot) stop consonant production in standard contemporary Persian. For this purpose, a production experiment was performed.
saeedeh taheri, mandana Nourbakhsh
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The structural motivation of palatalization
Fórum Linguístico, 2020 This paper is about the structural motivation of the palatalization of coronal stops in Brazilian Portuguese (BP) and cross-linguistically. It aims to explain why (a) coronal stop consonants are the typical targets of the process, (b) coronal stops are ...
Elisa Battisti, Ben Hermans
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source