Results 91 to 100 of about 106,679 (252)

Eco-conscious decision-support model for optimizing stopping patterns in the mass transit system

Engineering and Applied Science Research, 2022
The existing train operational efforts focus on need-based criteria for serving passenger demand while maintaining travel time satisfaction. Although mass transit contributes to reduced private vehicle fuel consumption, the current mass transit ...
Phattadon Khathawatcharakun, Charinee Limsawasd   +1 more
doaj  

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Revisiting the stopping rule for hepatitis C genotype 1 patients treated with peginterferon plus ribavirin.

PLoS ONE, 2012
BackgroundThe current stopping rule for peginterferon/ribavirin therapy in hepatitis C virus genotype-1 (HCV-1) patients is based on an early virological response (EVR, defined as >2 log(10) viral reduction at treatment week 12).
Ming-Lung Yu, Chen-Hua Liu, Chung-Feng Huang, Tai-Chung Tseng, Jee-Fu Huang, Chia-Yen Dai, Zu-Yau Lin, Shinn-Cherng Chen, Liang-Yen Wang, Suh-Hang Hank Juo, Wan-Long Chuang, Jia-Horng Kao   +11 more
doaj   +1 more source

XTRUDE: A Process‐Informed Framework for High‐Fidelity Analysis of Hydrogel Extrusion

Advanced Functional Materials, EarlyView.
Extrusion performance emerges from the interplay between material properties and processing conditions. XTRUDE (eXTrusion Rheology for Understanding and Defining Extrudability) recreates the extrusion environment with in situ pressure and temperature sensing, enabling characteristic pressure signatures to quantify extrusion‐specific phenomena and ...
Farhad Sanaei, Pascal Bertsch, Juliette Lafosse, Sander C. G. Leeuwenburgh, Mani Diba   +4 more
wiley   +1 more source

Magneto‐Ionic Devices With Polymer‐Based Electrolytes

Advanced Functional Materials, EarlyView.
Polymer electrolytes are introduced for magneto‐ionic devices based on hydroxide and hydrogen ions. The magneto‐ionic effect results in a pronounced voltage‐controlled variation of coercivity in both devices. The switching speed is in the range of 100 ms.
Markus Gößler, Richard Weber, Michael Sommer, Karin Leistner   +3 more
wiley   +1 more source

Intracrystalline Void‐Mediated Toughening of Brittle Crystals in Quail Eggshells

Advanced Functional Materials, EarlyView.
In quail eggshells, the high density and disordered arrangement of intracrystalline voids inhibit lattice cleavage, suppress long‐range crack propagation, and promote deformation twinning and quasi‐plasticity, serving as an essential toughening motif. We show that these voids remain within a narrow subcritical size range and therefore predominantly do ...
Jingxiao Zhong, Qihang Wang, Andre E. Vellwock, Sinuhe Perea Puente, Tingting Zhu, Jia Hui Lim, Kadda Medjoubi, Sebastian Hoerl, Erika Griesshaber, Wolfgang W. Schmahl, Yannicke Dauphin, Emeline Raguin, Peter Werner, Francesco Stellacci, Michael V. Swain, Peter Fratzl, Shahrouz Amini   +16 more
wiley   +1 more source

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Advanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang, Shunmuga Nathan Shunmuga Nainar, Bing‐Han Zhuang, Shun‐Mao Yang, Hong‐Cheu Lin, Yang‐Hsiang Chan   +5 more
wiley   +1 more source

S‐Nitrosothiols as Thiol‐Protecting Groups for Controlled Thiol‐Maleimide Crosslinking of Homogeneous Soft Hydrogels

Advanced Materials, EarlyView.
Rapid thiol‐maleimide addition frequently outpaces mixing, resulting in heterogeneous hydrogels. S‐nitrosothiols act as thiol‐protecting groups, allowing uniform mixing with maleimide‐functionalized polymers before gelation. Sodium thiosulfate or sodium ascorbate then regenerates thiols on demand, triggering controlled thiol‐maleimide crosslinking ...
Julian A. Serna, Michelle J. Iwohn, Maximilian Seifermann, Stefan Heißler, Maike Schliephake, Franziska Dopp, Claudia Muhle‐Goll, Pavel A. Levkin   +7 more
wiley   +1 more source

Descriptors to Dynamics: A Materials and Device Perspective on in‐Materio Physical Reservoir Computing for Neuromorphic Edge Intelligence

Advanced Materials, EarlyView.
Intrinsic material dynamics are harnessed as computational resources for neuromorphic in‐materio physical reservoir computing. Defects, ionic motion, interfaces, percolation, geometry, and biasing shape transient states that provide fading memory, nonlinearity, and high‐dimensional projection for simple readout. A descriptor‐to‐dynamics framework links
Kshitij RB Singh, Alif Syafiq Kamarol Zaman, Muzhen Xu, Yuki Usami, Saptarshi Das, Hirofumi Tanaka   +5 more
wiley   +1 more source

Predictive Performance of Anti-Lock Braking System with PID Controller Optimized by Gravitational Search Algorithm for a Quarter Car Model: Simulation Modeling and Control

Automotive Experiences
Anti-lock Braking Systems (ABS) are critical safety components in the passenger vehicles. The ABS prevents wheel lock-up during braking and maintains vehicle control.
Mohd Sabirin Rahmat, Fauzi Ahmad, Vimal Rau Aparow, Rizauddin Ramli, Sallehuddin Mohamed Haris, Mohd Anas Mohd Sabri, Mohd Anas Mohd Sabri, Meor Iqram Meor Ahmad, Mohd Muhyidin Mustafa   +8 more
doaj   +1 more source