Results 51 to 60 of about 127,543 (265)

Phase- and GVF-Based Level Set Segmentation of Ultrasonic Breast Tumors

Journal of Applied Mathematics, 2012
Automatically extracting breast tumor boundaries in ultrasound images is a difficult task due to the speckle noise, the low image contrast, the variance in shapes, and the local changes of image intensity.
Liang Gao, Xiaoyun Liu, Wufan Chen
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Belief Propagation Decoder With Multiple Bit-Flipping Sets and Stopping Criteria for Polar Codes

IEEE Access, 2020
Compared with successive cancellation list (SCL) decoders, belief propagation (BP)-based decoders suffer performance loss in middle-and high-signal-to-noise ratio (SNR) regions.
Jianyong Zhang, Muguang Wang
doaj   +1 more source

Legal regulation of the international road transport of passengers [PDF]

Zbornik Radova: Pravni Fakultet u Novom Sadu, 2017
Since March 2013 bus and coach passengers have a minimum set of rights when travelling in the European Union. Regulation 181/2011 concerning the rights of passengers in bus and coach transport applies to passengers traveling with regular services that ...
Đurđev Dušanka J.
doaj   +1 more source

The utility of STOP-BANG questionnaire in the sleep-lab setting [PDF]

Scientific Reports, 2019
AbstractPolysomnography (PSG) is considered the gold standard in obstructive sleep apnea-hypopnea syndrome (OSAS) diagnostics, but its availability is still limited. Thus, it seems useful to assess patients pre-diagnostic risk for OSAS to prioritize the use of this examination.
Wojciech Kuczyński, Łukasz Mokros, Aleksandra Stolarz, Piotr Białasiewicz   +3 more
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Symbolic Early Stopping in Neural Sequence Models via Mapper-Induced Symbolic Dynamics

Technologies
Early stopping is a standard form of implicit regularization in neural sequence models, but criteria based solely on validation loss can become unstable or weakly informative in noisy, non-stationary, or weakly separated regimes.
Ivan Tomilov, Rodion Zamotaev, Natalia Gusarova, Aleksandra Vatian   +3 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source