Results 111 to 120 of about 3,753,682 (301)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Happy days [music] : Sunday times song success /
, 1929 For voice and piano.; Caption title.; The item is a cutting from the newspaper the Sunday Times.; Also available online http://nla.gov.au/nla.mus ...
Fewster, Jack.
core
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
, 2006 A novel quickest detection model is proposed which can be seen as a generalization of the Bayesian changepoint setup. Suppose {(Xi,Yi)}i≥1 is a sequence of pairs of random variables, and that S is a stopping time with respect to {Xi}i≥1.
Urs Niesen +2 more
core
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
A Note on the Variance of a Stopping Time
The Annals of Statistics, 1987 Let \(\{S_ n=\sum^{n}_{1}X_ i\}_{n\geq 0}\) be a random walk with \(\mu =E X_ i>0\) and \(\sigma\) \(2=Var X_ ib\}\) be the hitting time of the set (b,\(\infty)\). \textit{T. L. Lai} and \textit{D. Siegmund} [Ann. Stat. 7, 60-76 (1979; Zbl 0409.62074)] showed that Var \(\tau\) (b)\(=b \sigma\) 2/\(\mu\) \(3+K/\mu\) \(2+o(1)\) as \(b\to \infty\), and ...
openaire +2 more sources
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
npj Computational MaterialsKnowing the rate at which particle radiation releases energy in a material, the “stopping power,” is key to designing nuclear reactors, medical treatments, semiconductor and quantum materials, and many other technologies.
Logan Ward +5 more
doaj +1 more source
InfrastructuresA motorcycle box intersection is a signalized intersection with advanced stop lines or stopping spaces intended for motorcycles, creating a waiting area in front of other vehicles.
Wachira Wichitphongsa +4 more
doaj +1 more source