Results 191 to 200 of about 6,354,906 (437)

Cobb-Douglas Production Function: The Case of a Converging Economy [PDF]

open access: yes
The Cobb-Douglas production function is often used to analyse the supply-side performance and measurement of a country’s productive potential. This functional form, however, includes the assumption of a constant share of labor in output, which may be too
Dana Hájková, Jaromír Hurník
core  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Research on the optimal scheduling of a multi-storage combined integrated energy system based on an energy supply grading strategy

open access: yesScientific Reports
As an important supporting technology for carbon neutrality strategy, the combination of an integrated energy system and hydrogen storage is expected to become a key research direction.
Na Zhang   +4 more
doaj   +1 more source

STUDIES ON THE MECHANISM OF NITROGEN STORAGE

open access: hybrid, 1949
Paul D. Bartlett   +2 more
openalex   +1 more source

Some Characterizations of Convex Interval Games [PDF]

open access: yes
This paper focuses on two characterizations of convex interval games using the notions of superadditivity and exactness, respectively. We also relate big boss interval games with concave interval games and obtain characterizations of big boss interval ...
Rodica Branzei   +2 more
core  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Dynamic Optimization of Storage Systems Using Reinforcement Learning Techniques [PDF]

open access: yesarXiv
The exponential growth of data-intensive applications has placed unprecedented demands on modern storage systems, necessitating dynamic and efficient optimization strategies. Traditional heuristics employed for storage performance optimization often fail to adapt to the variability and complexity of contemporary workloads, leading to significant ...
arxiv  

The Impact of EU Regional Support on Growth and Employment [PDF]

open access: yes
In this paper the authors assess the impact of structural funds on the per capita GDP and employment convergence process of 145 European regions over 1989–1999. This paper goes beyond the recent contributions on European regional policies and convergence
Julie Le Gallo, Sandy Dall’erba
core  

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