Results 51 to 60 of about 6,857,881 (395)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

An infrared, Raman, and X-ray database of battery interphase components

Scientific Data
Further improvements to lithium-ion and emerging battery technologies can be enabled by an improved understanding of the chemistry and working mechanisms of interphases that form at electrochemically active battery interfaces. However, it is difficult to
Lukas Karapin-Springorum, Asia Sarycheva, Andrew Dopilka, Hyungyeon Cha, Muhammad Ihsan-Ul-Haq, Jonathan M. Larson, Robert Kostecki   +6 more
doaj   +1 more source

Energy storage: The future enabled by nanomaterials

Science, 2019
Thinking small to store more From mobile devices to the power grid, the needs for high-energy density or high-power density energy storage materials continue to grow.
E. Pomerantseva, F. Bonaccorso, Xinliang Feng, Yi Cui, Y. Gogotsi   +4 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Catholyte engineering to release the capacity of iodide for high‐energy‐density iodine‐based redox flow batteries

SusMat, 2023
Due to the high solubility, high reversibility, and low cost of iodide, iodine‐based redox flow batteries (RFBs) are considered to have great potential for upscaling energy storage.
Bo Lu, Minghui Yang, Mei Ding, Su Yan, Weizhe Xiang, Yuanhang Cheng, Hu Fu, Zhizhao Xu, Chuankun Jia   +8 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Progress in thermal stability of all‐solid‐state‐Li‐ion‐batteries

InfoMat, 2021
Thermal safety is one of the major issues for lithium‐ion batteries (LIBs) used in electric vehicles. The thermal runaway mechanism and process of LIBs have been extensively studied, but the thermal problems of LIBs remain intractable due to the ...
Yujing Wu, Shuo Wang, Hong Li, Liquan Chen, Fan Wu   +4 more
doaj   +1 more source

HOMER-Based Multi-Scenario Collaborative Planning for Grid-Connected PV-Storage Microgrids with Electric Vehicles [PDF]

, 2023
Yifan Zhang, Shiye Yan, Wenqian Yin, Chao Wu, Jilei Ye, Yuping Wu, Lili Liu   +6 more
openalex   +1 more source

Lysosomal Storage Diseases

Translational Science of Rare Diseases, 2016
Lysosomes are cytoplasmic organelles that contain a variety of different hydrolases. A genetic deficiency in the enzymatic activity of one of these hydrolases will lead to the accumulation of the material meant for lysosomal degradation. Examples include glycogen in the case of Pompe disease, glycosaminoglycans in the case of the mucopolysaccharidoses,
Ferreira, Carlos R., Gahl, William A.
openaire   +3 more sources