Results 171 to 180 of about 909,986 (318)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Assessment of PEG-Asparaginase and Erwinia Asparaginase Activity Under Variable Storage Conditions. [PDF]

Pharmaceutics
Friederici Dahl SA, Hoffmann-Lücke E, Klug Albertsen B, Greibe E.   +3 more
europepmc   +1 more source

Production Planning and Inventories Optimization: A Backward Approach in the Convex Storage Cost Case. [PDF]

We study the deterministic optimization problem of a profit-maximizing firm which plans its sales/production schedule. The firm controls both its production and sales rates and knows the revenue associated to a given level of sales, as well as its ...
Tahraoui, Rabah, Jouini, Elyès, Chazal, Marie   +2 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Influence of storage conditions on the mechanical properties of intermaxillary elastics. [PDF]

Prog Orthod
Urbanova W, Voborná I, Šrolerová T, Sluka D, Poláčková P, Dubovská I.   +5 more
europepmc   +1 more source

Impedance Reshaping Strategy for Battery Energy Storage Systems Based on Partial Power Conversion

To avoid additional component losses while significantly improving the energy conversion efficiency of battery energy storage systems, the application of series-connected partial power converter (S-PPC) technology in battery energy storage systems is ...
Xiangxin Xi, Ming Li, Yucheng Wu, Haibo Liu, Long Jing, Baizheng Xu   +5 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Storage conditions and antiviral efficacy of yeast-derived vacuoles on T4 virus. [PDF]

Microbiol Spectr
Kim T, Jeong J-H, Kim Y-H, Min J.
europepmc   +1 more source

The Effect of Storage Condition on the Respiration of Soybean

JOURNAL of the JAPANESE SOCIETY of AGRICULTURAL MACHINERY, 2003
SOROUR, Hussain, UCHINO, Toshitaka
openaire   +1 more source