Results 91 to 100 of about 7,006,519 (348)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Introduction

Grounded Theory Review: An International Journal, 2013
Memos are neglected as a GT procedure. Memos are where the emergent concepts and theoretical ideas are generated and stored when doing GT analysis. They are a neglected procedure mostly in writing about doing GT, yet they are vital to GT analysis for ...
Barney G. Glaser
doaj  

Personalized online information search and visualization

BMC Medical Informatics and Decision Making, 2005
Background The rapid growth of online publications such as the Medline and other sources raises the questions how to get the relevant information efficiently. It is important, for a bench scientist, e.g., to monitor related publications constantly. It is
Orthner Helmuth F, Chen Dongquan, Sell Susan M   +2 more
doaj   +1 more source

Electronically Stored Information: Balancing Free Discovery With Limits on Abuse [PDF]

, 2009
The Federal Rules of Civil Procedure (the Rules) have long sought to limit abuses that developed under the traditional presumption favoring free discovery.
Groot, Patricia
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Introduction: Free Style Memoing

Grounded Theory Review: An International Journal, 2013
Memos are neglected as a GT procedure. Memos are where the emergent concepts and theoretical ideas are generated and stored when doing GT analysis. They are a neglected procedure mostly in writing about doing GT, yet they are vital to GT analysis for ...
Barney G. Glaser, PhD, Hon. PhD
doaj  

The Advent of Semi-Elective Lung Transplantation—Prolonged Static Cold Storage at 10°C

Transplant International
Since the early days of clinical lung transplantation the preservation of donor organs has become a fairly standardized procedure and most centers do follow similar processes. This includes the use of low-potassium high dextran flush solutions and static
K. Hoetzenecker, A. Benazzo, S. Schwarz, S. Keshavjee, M. Cypel   +4 more
doaj   +1 more source

Visuelle Analyse von stored procedures in Datenbanksystemen [PDF]

, 2013
In many big database systems Stored Procedures are used to efficiently transform the data. Over time these procedures become a difficult system with complex and obscure dependencies. Analyses of failures and for optimization purposes can only be done with huge manual effort and in-depth knowledge of the system.
openaire   +1 more source

Attention Focusing for Neural Machine Translation by Bridging Source and Target Embeddings

, 2018
In neural machine translation, a source sequence of words is encoded into a vector from which a target sequence is generated in the decoding phase. Differently from statistical machine translation, the associations between source words and their possible
Branco, António, Kuang, Shaohui, Li, Junhui, Luo, Weihua, Xiong, Deyi   +4 more
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source