Results 121 to 130 of about 2,257,928 (251)

Estimation of population density and spatial pattern of stored paddy rice insect species using un-baited traps

open access: yes, 2004
Studies were conducted in five paddy rice stores and one silo used for rice storage to determine the insect species associated with stored rice, their abundance and spatial pattern from November 2002 to April 2003.
Adler, Cornel   +5 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Pemrograman stored procedure pada mysql

open access: yes
Kemampuan baru yang disediakan oleh MySQL berupa stored procedure, function dan trigger atau disebut stored program tidak mudah dipelajari dan digunakan oleh parapengembang program aplikasi yang menggunakan MySQL.
Privida Kristiono
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Atividade enzimática em plântulas de eucalyptus grandis provenientes de sementes envelhecidas artificialmente e naturalmente

open access: yesCiência Florestal, 2000
This research studied the standard procedure developed for crop seeds to examine the biochemical processes in accelerated aging seeds (kept for 96 hours at 42ºC and 100% RH) and stored seeds (from 5, 10 and 15 years) using isoenzyme electrophoresis and
Maria Letícia Camargo Pereira de   +4 more
doaj  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

First experience and clinical results of DSAEK utilizing the pre-cut ultrathin grafts

open access: yesОфтальмохирургия, 2013
Purpose. To evaluate the clinical functional efficiency of pre-cut donor corneas stored in the original preservation medium for the Ultrathin DSAEK procedure. Material and methods.
B.E. Malyugin,   +4 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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