Results 211 to 220 of about 2,044,947 (320)

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Solar-driven thermochemical tri-generation of electricity, hydrogen, and green ammonia with AI-assisted triple-objective optimization. [PDF]

Sci Rep
Ayadi B, Kriaa K, Alsayah AM, Sadeq AM, Singh NSS, Aich W, Hajlaoui K, Mostafa L.   +7 more
europepmc   +1 more source

Optimizing Stored Procedures: Advanced Techniques for Improved SQL Performance

, 2019
Vishnupriya S Devarajulu
openalex   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

A ferroelectric-memristor memory for both training and inference. [PDF]

Nat Electron
Martemucci M, Rummens F, Malot Y, Hirtzlin T, Guille O, Martin S, Carabasse C, Vincent AF, Saïghi S, Grenouillet L, Querlioz D, Vianello E.   +11 more
europepmc   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

A compendium of temperature and salinity profiles and discrete nutrients from selected NOAA programs in Alaska. [PDF]

Sci Data
Mordy CW, Pelland NA, Bell SW, Cheng W, Gann JC, Hermann AJ, McFarland CR, Nielsen JM, Stabeno PJ, Sullivan ME, Wisegarver ES.   +10 more
europepmc   +1 more source

Freezing procedure without thrombin activation to retain and store growth factors from platelet concentrates

, 2011
Ching‐Hwa Gau, E‐Chin Shen, Hsiao‐Pei Tu, Hsien‐Chung Chiu, Earl Fu, Wei‐Nan Wang, Cheng‐Yang Chiang   +6 more
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source