Results 241 to 250 of about 738,126 (291)

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Documented Paternity Despite Azoospermia Post-vasectomy. [PDF]

Cureus
Bernardes T, Wu TY, Greves CC, Carlan S.
europepmc   +1 more source

Regulating Protein Immobilization During Cell‐Free Protein Synthesis in Hyaluronan Microgels

Advanced Biology, EarlyView.
Bifunctional microgels carrying a linear DNA template and Ni2+‐activated NTA moieties are used as platform for cell‐free protein synthesis and in situ protein immobilization. By varying the concentration of NTA moieties in the microgels, the amount of GFP‐His immobilized inside the microgel and released to the microgel environment can be regulated ...
Anika Kaufmann, Kateryna Ivanova, Julian Thiele   +2 more
wiley   +1 more source

Evaluation of a second-generation intercostal extravascular implantable cardioverter defibrillator lead with a pectoral pulse generator for sensing, defibrillation, and anti-tachycardia pacing. [PDF]

Europace
Doshi SK, Knops RE, Ebner A, Husby M, Marcovecchio A, Sanghera R, Scheck D, Burke MC.   +7 more
europepmc   +1 more source

Scaling Up Synthetic Cell Production Using Robotics and Machine Learning Toward Therapeutic Applications

Advanced Biology, EarlyView.
Synthetic cells (SCs) hold great promise for biomedical applications, but manual production limits scalability. This study presents an automated method for large‐scale SC synthesis, integrating robotic liquid handling and machine learning‐driven high‐throughput characterization.
Noga Sharf‐Pauker, Ido Galil, Omer Kfir, Gal Chen, Rotem Menachem, Jeny Shklover, Avi Schroeder, Shanny Ackerman   +7 more
wiley   +1 more source

Sterilization and Disinfection: Ensuring Infection Control in Dental Practices. [PDF]

Cureus
Patiño-Marín N, Villa García LD, Aguirre López EC, Medina-Solís CE, Martínez Zumarán A, Martínez Rider R, Márquez Preciado R, Rosales García P, Salas Orozco MF.   +8 more
europepmc   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

mRNA extracted from frozen buffy coat samples stored long term in tubes with no RNA preservative shows promise for downstream sequencing analyses. [PDF]

PLoS One
Bovinder Ylitalo E, Vidman L, Harlid S, Van Guelpen B.   +3 more
europepmc   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source