Results 51 to 60 of about 2,044,947 (320)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Fits to data for a stored uncooled polarized deuteron beam

open access: yes, 2013
I perform tracking simulations to fit various measurements of the polarization for a stored uncooled polarized deuteron beam, published in the recent paper by Benati et. al (P. Benati {\em et al.}, {\it Phys. Rev. ST Accel. Beams} {\bf 15}, 124202 (2012))
Mane, S. R.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Hump Yard Track Allocation with Temporary Car Storage [PDF]

open access: yes, 2010
In rail freight operation, freight cars need to be separated and reformed into new trains at hump yards. The classification procedure is complex and hump yards constitute bottlenecks in the rail freight network, often causing outbound trains to be ...
Bohlin, Markus   +3 more
core   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Semi-automatic annotation process for procedural texts: An application on cooking recipes [PDF]

open access: yes, 2012
Taaable is a case-based reasoning system that adapts cooking recipes to user constraints. Within it, the preparation part of recipes is formalised as a graph.
Ber, Florence Le   +4 more
core   +2 more sources

Compressed matched filter for non-Gaussian noise

open access: yes, 2013
We consider estimation of a deterministic unknown parameter vector in a linear model with non-Gaussian noise. In the Gaussian case, dimensionality reduction via a linear matched filter provides a simple low dimensional sufficient statistic which can be ...
Vovnoboy, Jakob, Wiesel, Ami
core   +1 more source

Developing an ontology for the domain name system [PDF]

open access: yes, 2005
©2005 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any ...
Coddington, P.   +2 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Development of a Cryopreservation Procedure Employing a Freezer Bag for Pancreatic Islets Using a Newly Developed Cryoprotectant

open access: yesCell Transplantation, 2001
One of the most important requirements for success in clinical islet transplantation is the use of a large number of viable donor islets. To achieve this, the ability to cryopreserve islets and to establish an islet bank are critical.
Masaaki Miyamoto   +9 more
doaj   +1 more source

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