Results 51 to 60 of about 7,063,150 (343)

Stool sample storage conditions for the preservation of Giardia intestinalis DNA

Memorias do Instituto Oswaldo Cruz, 2012
Stool is chemically complex and the extraction of DNA from stool samples is extremely difficult. Haemoglobin breakdown products, such as bilirubin, bile acids and mineral ions, that are present in the stool samples, can inhibit DNA amplification and ...
Salih Kuk, Suleyman Yazar, Ulfet Cetinkaya   +2 more
doaj   +1 more source

Compressed matched filter for non-Gaussian noise

, 2013
We consider estimation of a deterministic unknown parameter vector in a linear model with non-Gaussian noise. In the Gaussian case, dimensionality reduction via a linear matched filter provides a simple low dimensional sufficient statistic which can be ...
Vovnoboy, Jakob, Wiesel, Ami
core   +1 more source

Static flux bias of a flux qubit using persistent current trapping [PDF]

, 2006
Qubits based on the magnetic flux degree of freedom require a flux bias, whose stability and precision strongly affect the qubit performance, up to a point of forbidding the qubit operation.
Chiarello F, Devoret M H Wallraff A Martinis J M, Fabio Chiarello, Guido Torrioli, Kutsuzawa T Saito S Tanaka H Nakano H Semba K Takayanagi H, Maria Gabriella Castellano, Pasquale Carelli, Wendin G Shumeiko V S   +7 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Toward accurate polynomial evaluation in rounded arithmetic [PDF]

, 2005
Given a multivariate real (or complex) polynomial $p$ and a domain $\cal D$, we would like to decide whether an algorithm exists to evaluate $p(x)$ accurately for all $x \in {\cal D}$ using rounded real (or complex) arithmetic.
Demmel, James, Dumitriu, Ioana, Holtz, Olga   +2 more
core   +4 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Semi-automatic annotation process for procedural texts: An application on cooking recipes [PDF]

, 2012
Taaable is a case-based reasoning system that adapts cooking recipes to user constraints. Within it, the preparation part of recipes is formalised as a graph.
Ber, Florence Le, Dufour-Lussier, Valmi, Lieber, Jean, Meilender, Thomas, Nauer, Emmanuel   +4 more
core   +2 more sources

Fits to data for a stored uncooled polarized deuteron beam

, 2013
I perform tracking simulations to fit various measurements of the polarization for a stored uncooled polarized deuteron beam, published in the recent paper by Benati et. al (P. Benati {\em et al.}, {\it Phys. Rev. ST Accel. Beams} {\bf 15}, 124202 (2012))
Mane, S. R.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source