Results 91 to 100 of about 2,068,156 (308)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Informed Consent to Address Trust, Control, and Privacy Concerns in User Profiling [PDF]

open access: yes, 2005
More and more, services and products are being personalised or\ud tailored, based on user-related data stored in so called user profiles or user\ud models.
Geest, Thea van der   +2 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Effect of locally available spices on the organoleptic and storage periods of Heterotis niloticus [PDF]

open access: yes, 2005
Investigation were carried out on the effect of some locally available species in the enhancement of the organoleptic quality and the storage periods of smoked Heterotis niloticus using Pprosopis africana as common smoke sources.
Ogbe, F.G., Okpale, E.O., Tiamiyu, L.O.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Mathematical modeling of the drying characteristics and economic analysis of Hake fish using Smoking Kiln

open access: yesJournal of Research in Agriculture and Food Sciences
Aim/Background: This study aims to provide a detailed assessment on the mathematical modelling of the drying characteristics of Hake Fish using smoking kiln.
Taiwo Oluwatoyin AJAO   +9 more
doaj   +1 more source

Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) PARM tape user's guide [PDF]

open access: yes
The Scanning Multichannel Microwave Radiometer (SMMR) instrument, onboard the Nimbus-7 spacecraft, collected data from Oct. 1978 until Jun. 1986. The data were processed to physical parameter level products.
Cebula, R. P.   +5 more
core   +1 more source

Improvement of seed germination of Fagus orientalis Lipsky [PDF]

open access: yes, 2003
This thesis was seeking two main approaches for improvement of seed germination of oriental beech, a timber producing species in Hyrcanian forests in northern Iran. Germination behavior of beechnuts was enhanced either by decreasing the dormancy breakage
Soltani, Ali
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Feromônios associados aos coleópteros-praga de produtos armazenados Pheromones associated to coleopteran pests in stored products

open access: yesQuímica Nova, 2005
One strategy to overcome risks of insecticide-based control in agriculture is to use semiochemicals. In the case of pheromones, these specific compounds can be applied in traps to detect and monitor the occurrence, abundance and distribution of insect ...
Marcos Antônio Barbosa Moreira   +2 more
doaj   +1 more source

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