Results 111 to 120 of about 2,072,425 (306)

Pendugaan Masa Kadaluwarsa Dendeng Lumat Ikan Patin (Pangasius Hypophthalmus) pada Kemasan Aluminium Foil [PDF]

open access: yes, 2014
The research was to estimate the shelf life of catfish dendeng stored at room temperature (270C) and refrigerated temperature (50C). About 15 kg catfish weighing 600-800 gr each was obtained from a fish market in Pekanbaru. Two groups of dendeng prepared
Dahlia, D. (Dahlia)   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Assessing the long-distance repellency of long-lasting insecticide netting to a suite of post-harvest insects [PDF]

open access: yes, 2018
Insects are our main competitors for food on the planet (1). In fact, growers lose 10-30% of crops during storage, processing, and marketing after harvest each year to stored product insects (2,3).
Alonso, Alicia Amairani   +2 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) PARM tape user's guide [PDF]

open access: yes
The Scanning Multichannel Microwave Radiometer (SMMR) instrument, onboard the Nimbus-7 spacecraft, collected data from Oct. 1978 until Jun. 1986. The data were processed to physical parameter level products.
Cebula, R. P.   +5 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Extraction and Characterization of Chitosan from Snail Shells (Achatina fulica) [PDF]

open access: yesJournal of Food Quality and Hazards Control
Background: Chitosan due to biodegradable and non-toxic characteristics has versatile applications. Extraction and characterization of Chitosan from Snail Shells In January, 2023 Achatina fulica was performed.
S. Tertsegha   +4 more
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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