Results 231 to 240 of about 1,110,243 (298)

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

Refractory ventricular tachycardia storm with 42 ICD shocks in 24 h: A case report. [PDF]

Med Int (Lond)
Adrejiya P, Neshat N, Qamar AR, Suthar H, Orjioke N, Thandra A, Patel D.   +6 more
europepmc   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Cardiac Sympathetic Denervation for Termination of Ventricular Tachycardia Storm: A Multidisciplinary Case. [PDF]

JACC Case Rep
Cui C, Wei K, Zhou X, Wu W, Ju W, Chen M.   +5 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Translation, Cross-Cultural Adaptation, and Validation of the Storm Fear Questionnaire in Brazilian Pregnant Women Exposed to an Extreme Climate Event. [PDF]

Brain Sci
Garcia MG, Baldi BBC, Giuberti P, Chrusciel JH, Berlaver ST, Machado GC, Lodi MA, Kristensen CH, Tractenberg SG, Grassi-Oliveira R, Viola TW.   +10 more
europepmc   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

A Case of Thyroid Storm With Fatal Outcome due to Liver Failure. [PDF]

Case Rep Pathol
Suzuki K, Makiuchi S, Kishida Y.
europepmc   +1 more source

<i>Eupatorium lindleyanum</i> DC. Suppresses Cytokine Storm by Inhibiting NF-κB and PI3K-Akt Signaling in Sepsis-Associated and Virus-Related Acute Lung Injury. [PDF]

Curr Issues Mol Biol
Luo C, He P, Yang Y, Xia L, Xu W, Zou D, Feng Y, Duan L, Deng J, Jing Y, Luo X.   +10 more
europepmc   +1 more source

Proteomic phenotyping with machine learning for cardiovascular outcomes in haemodialysis: insights from the AURORA trial. [PDF]

Eur Heart J Digit Health
Salib M, Girerd S, Pinet F, März W, Scharnagl H, Massy ZA, Leroy C, Duarte K, Bresso E, Lacomblez C, Jardine AG, Schmieder RE, Fellstrom B, Lopez-Andres N, Rossignol P, Zannad F, Girerd N.   +16 more
europepmc   +1 more source