Results 191 to 200 of about 77,372 (282)

WxC-Bench: A Novel Dataset for Weather and Climate Downstream Tasks. [PDF]

Sci Data
Shinde R, Ankur K, Phillips CE, Gupta A, Pfreundschuh S, Roy S, Kirkland S, Gaur V, Kolluru V, Lin A, Trital P, Sheshadri A, Nair U, Maskey M, Ramachandran R.   +14 more
europepmc   +1 more source

Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices

Advanced Science, EarlyView.
This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee, Oliver James, Gaeun Jung, Doyun Lee, Yee‐Joon Kim   +4 more
wiley   +1 more source

Observed physical and biogeochemical variability due to tropical cyclone Mocha using glider observations in the Bay of Bengal. [PDF]

Sci Rep
Thangaprakash VP, Sureshkumar N, Srinivas KS, Chandramouli A, Theagarajan S, Rajasekhar Y, Kumar V, Kumar MR.   +7 more
europepmc   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Multiplexed Chromatin Analysis Using Optical Spectroscopic Statistical Nanosensing. [PDF]

ACS Photonics
Su Y, Almassalha LM, Acosta N, Dunton CL, Medina KI, Liwag EP, Wang G, Backman V.   +7 more
europepmc   +1 more source

The POLCOMS-WAM Wave-Current Interaction Model: development and performance in the NW Mediterranean [PDF]

, 2008
Bolanos, R., Monbaliu, J., Osuna, P, Sanchez-Arcilla, A., Wolf, J.   +4 more
core  

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

One-click reconstruction in single-molecule localization microscopy via experimental parameter-aware deep learning. [PDF]

Npj Imaging
Saguy A, Xiao D, Narayanasamy KK, Nakatani Y, Saliba N, Gagliano G, Gustavsson AK, Heilemann M, Shechtman Y.   +8 more
europepmc   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

Postoperative transient sympathetic storm after endoscopic third ventriculostomy with choroid plexus cauterization in pediatric hydrocephalus. [PDF]

Saudi J Anaesth
Guo G, Cao H.
europepmc   +1 more source