Results 121 to 130 of about 411,390 (328)

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Spatiotemporal SWMM-LSTM surrogate modeling for efficient node-level water depth and inflow prediction in urban drainage networks

Cambridge Prisms: Water
Extreme weather events, combined with human-induced factors, such as expanding impervious surfaces and inadequate drainage infrastructure, are driving escalating urban flood risks worldwide.
Nima Zafarmomen, Vidya Samadi, Edoardo Borgomeo   +2 more
doaj   +1 more source

Effectiveness of Hydraulic and Hydrologic Parameters in Assessing Storm System Flooding

Advances in Civil Engineering, 2018
Storm sewer systems face many challenges in urban areas, in particular those systems which are old and surpassing their design period. This study has used data from an urbanized, subcatchment covering 360 ha of dead run watershed in the Alkadeer district,
Basim K. Nile
doaj   +1 more source

Water Quality Sampling, Analysis and Annual Load Determinations for TSS, Nitrogen and Phosphorus at the Wyman Road Bridge on the White River [PDF]

, 2003
A water quality sampling station was installed at the Wyman Road Bridge just below the confluence of the three main forks of the Upper White River in January 2000. This station is coordinated with the USGS gaging station at the same location.
Cash, Wade, Nelson, Marc
core   +2 more sources

Microfluidic Electrochemical Biosensor for the Detection of Platelet Factor 4 Antibody‐Mediated Thrombotic Disorders

Advanced Science, EarlyView.
A microfluidic electrochemical biosensor enables sensitive and specific detection of antibodies associated with vaccine‐induced immune thrombotic thrombocytopenia (VITT) and heparin‐induced thrombocytopenia (HIT). The platform uses two antigen targets— platelet factor 4 (PF4) and cross‐linked‐PF4 (c‐PF4)—and microliter volumes of patient sera to ...
Diana F. Cedillo‐Alcantar, Adam Kanack, Seonhwa Lee, Alan M. Gonzalez‐Suarez, Kihak Gwon, Emily Mauch, Thi Thanh‐Qui Nguyen, Anand Padmanabhan, Alexander Revzin   +8 more
wiley   +1 more source

A comprehensive investigation of storm surge-induced urban flooding in Macao during Typhoon Hato in 2017

Engineering Applications of Computational Fluid Mechanics
A comprehensive understanding of the processes of storm surge and flooding induced by typhoons is crucial for the development of effective emergency plans and risk management strategies. This study employed the three-dimensional coastal ocean circulation
Jinlan Guo, Shan Huang, Mingming Ge, Joseph Hun Wei Lee   +3 more
doaj   +1 more source

Estudo do comportamento hidráulico da Bacia do Paracuri em Belém (PA) utilizando o programa Storm Water Management Model

, 2015
Estuda-se o comportamento hidraulico do sistema de drenagem da Bacia do Paracuri, no municipio de Belem (PA), com o uso do codigo computacional livre Storm Water Management Model (SWMM), sendo simulados dois cenarios, ambos referentes a ocorrencia de uma
M. Vinagre, Alberto Carlos de Melo Lima, D. M. D. L. Junior   +2 more
semanticscholar   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

What Explains the Incidence of the Use of a Common Sediment Control on Lots with Houses Under Construction? [PDF]

To analyze compliance with one aspect of the regulation of stormwater discharge, we estimate a random-utility model of the probability that a builder uses a silt fence to control sediments on a lot with a house under construction in an urbanizing county ...
Campbell, Wallace A., Haselbach, Liv M., Hayes, John C., Sessions, William T., Templeton, Scott R.   +4 more
core   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source