Results 141 to 150 of about 411,390 (328)

Florida's Coastal and Ocean Future: An Updated Blueprint for Economic and Environmental Leadership [PDF]

, 2012
Florida's coastal and marine habitats and numerous ecological and economic resources provide invaluable assetsto the millions of people who live in Florida or visit the state each year. The coast is Florida's economic engine.

core  

Modification Strategies of Carbon‐Based Electrodes From Structural Regulation to Multifunctional Integration

Advanced Science, EarlyView.
Tracing the evolution from structural regulation to multifunctional integration, this paper systematically analyzes modification strategies for carbon‐based electrodes. It evaluates how element doping, surface functionalization, and composite material design affect the electrode performance, and offers perspectives on future applications and challenges
Yunlei Wang, Shitao Dou, Yifan Wu, Mingguang Wang, Taibin Wu   +4 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Accelerating Urban Drainage Simulations: A Data-Efficient GNN Metamodel for SWMM Flowrates

Engineering Proceedings
Computational models for water resources often experience slow execution times, limiting their application. Metamodels, especially those based on machine learning, offer a promising alternative.
Alexander Garzón, Zoran Kapelan, Jeroen Langeveld, Riccardo Taormina   +3 more
doaj   +1 more source

Semi-distributed Storm Water Management Model for Urban Flood Mitigation and Management through LID's

, 2019
Conference ...
Sinha, Manish Kumar, Sharma, Monika, Gouraha, Sushmita   +2 more
openaire   +1 more source

Evaluation of Continuous Monitoring as a Tool for Municipal Stormwater Management Programs [PDF]

, 2018
The purpose of this study is to evaluate the uncertainty attributable to inadequate temporal sampling of stormwater discharge and water quality, and understand its implications for meeting monitoring objectives relevant to municipal separate storm sewer ...
Dymond, Randel L., Lohani, Vinod K., McDonald, Walter M.   +2 more
core   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Concepts and applications of the Flanders Hydrological Model environment

E3S Web of Conferences, 2016
Today, water authorities face a set of water management challenges, related to new European policies, climate change adaptation, land use planning, urban wastewater and storm water management.
Vansteenkiste Thomas, Dewelde Joost, Cabus Pieter, de Jongh Inge, Cauwenberghs Kris   +4 more
doaj   +1 more source

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of BiTE‐Secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

High-Resolution Modeling of Storm Surge Response to Typhoon Doksuri (2023) in Fujian, China: Impacts of Wind Field Fusion, Parameter Sensitivity, and Sea-Level Rise

Journal of Marine Science and Engineering
To quantitatively assess the storm surge induced by Super Typhoon Doksuri (2023) along the complex coastline of Fujian Province, a high-resolution Finite-Volume Coastal Ocean Model (FVCOM) was developed, driven by a refined Holland–ERA5 hybrid wind field
Ziyi Xiao, Yimin Lu
doaj   +1 more source