Results 201 to 210 of about 636,342 (244)

Lab‐Scale Fabrication Process Selection for Soft Robotics: Benchmarking, Tradeoffs, and Guidelines for Formative Manufacturing of Soft Silicone Components

Advanced Intelligent Systems, EarlyView.
Fabrication shapes soft robot performance, but benchmarking data and selection guidelines remain scarce. We fabricate silicone actuators using two molding techniques and three mold types, characterizing them with cycle testing, microscopy, profilometry, and 3D imaging. Applying our lab‐scale, soft robotics‐specific fabrication evaluation criteria shows
Charlotte M. Folinus, Daniel Massimino, Cat Arase, Kaitlyn P. Becker   +3 more
wiley   +1 more source

Differential Water Networks Guide Selectivity Optimization of a Cell Active BPTF Inhibitor in Neuroblastoma

Angewandte Chemie, EarlyView.
BZ2 is a second‐generation Bromodomain PHD finger Transcription Factor (BPTF) inhibitor with improved selectivity over Class I and Class IV BRD off‐targets identified in our previously reported inhibitor, BZ1. Structural analyses reveal that water network engagement is key to this selectivity.
Kesavan Babu, Chun‐Ju Tsou, Sourav Das, Liying Fan, Anasuya Pal, Molly Sneddon, Timothy R. Stachowski, Priyanka Samanta, Stanley Nithianantham, Caroline Buchholz, Shi Zhang, Xiang Fu, Rahul S. Kathayat, Wenwei Lin, Yongtao Li, Lei Yang, Taosheng Chen, Marcus Fischer, Anang A. Shelat, William C. K. Pomerantz   +19 more
wiley   +2 more sources

Case Report: Recurrent pelvic gestational choriocarcinoma arising from an occult complete mole unmasked by short tandem repeat genotyping. [PDF]

Front Oncol
Qiu H, Chen T, Ma F, Hu W, Lu X, Ma J, Du Y, Yue X.   +7 more
europepmc   +1 more source

Expanding the Utility of Exome Sequencing in Preventive and Population Genetics

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Carrier screening is a long‐standing genetic testing process offered to at‐risk couples, with or without a family history, who might have pregnancies affected by an autosomal recessive (AR) or X‐linked (XL) disorder. A total of 276 unrelated individuals, initially referred for rare disorder screening by clinicians, were enrolled in this study ...
Charilaos Kostoulas, Athanasia Sesse, Ioanna Bouba, Robert Najdecki, Spyridon Konitsiotis, Sofia Markoula, Ioannis Georgiou   +6 more
wiley   +1 more source

Maximizing Active Site Density in Tin Single‐Site Catalysts for Selective Carbon Dioxide to Formate Electroreduction

Angewandte Chemie, EarlyView.
High‐loading tin single‐site catalysts (>7.5 wt.% Sn) are synthesized using a nitrogen‐enriched carbon scaffold and mechanochemically assisted pyrolysis to stabilize atomically dispersed Sn. The resulting Sn/N‐C‐M catalyst enables highly selective CO2‐to‐formate conversion (>90% FE across 50–500 mA cm−2) with long‐term durability and operando‐verified ...
Katharina Potemkin, Soressa Abera Chala, Chia‐Yu Chang, Keseven Lakshmanan, Meng‐Che Tsai, Tobias Rios Studer, Elnaz Ebrahimi, Nico Achenbach, Rongji Liu, Johannes Biskupek, Ute Kaiser, Bing Joe Hwang, Carsten Streb   +12 more
wiley   +2 more sources

Inhibition of cyclin-dependent kinase 8 modulates chondrocyte transition to hypertrophy and provides in vivo protection against spontaneous osteoarthritis. [PDF]

Bone Res
Wells LM, Keen JAC, Sharma A, Marr N, Hansen R, Pereira JS, Roe T, Roberts HC, Oppermann U, Clarke PA, Pitsillides AA, Roberts SJ.   +11 more
europepmc   +1 more source

Evaluation of therapeutic effects of D‐limonene following orchiopexy in the rat model of cryptorchidism

Animal Models and Experimental Medicine, EarlyView.
D‐limonene supplementation enhances testicular recovery following orchiopexy in a rat model of bilateral cryptorchidism. Treatment with D‐limonene reduces oxidative stress (↓MDA, ↑SOD, ↑GPx, ↑TAC), downregulates pro‐apoptotic proteins (↓TNF‐α, ↓BAX, ↓Caspase‐3), and upregulates anti‐apoptotic Bcl‐2 expression.
Arman Norouzi‐Ghalehbala, Mohammadjavad Rezaei‐Varmaziar, Majid Taati, Ali Soleimanzadeh, Abbas Raisi, Farshid Davoodi, Amir Ali Shahbazfar   +6 more
wiley   +1 more source

BAM-STR: A Bio-Inspired Soft Tensegrity Robot Driven by McKibben Pneumatic Artificial Muscles. [PDF]

Micromachines (Basel)
Jiang Y, Yang X, Zuo Z, Chen Y, Zhang S, Jiang H, Gu S, Peng Y.   +7 more
europepmc   +1 more source

Circumscribed Meningeal Melanocytic Neoplasms: CNS WHO Grade, Molecular Profile, and Clinical Outcomes. [PDF]

Brain Pathol
Zhu Y, Karbhari N, Kaufmann TJ, Raghunathan A, Ida CM, Zepeda-Mendoza CJ, Dryden IJ, Salamat S, Atherton C, Jenkins SM, Markovic SN, Sener UT, Giannini C.   +12 more
europepmc   +1 more source

A Biomedical Researcher's Guide for Analyzing Short Tandem Repeat (STR) Genotypes of Human Cell Lines and in Vitro Tissue Samples Using Three Standard Authentication Algorithms. [PDF]

Curr Protoc
Korch CT.
europepmc   +1 more source