Results 71 to 80 of about 10,183,589 (342)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Strain-induced modulation of Dirac cones and van Hove singularities in twisted graphene bilayer
, 2014 By means of atomistic tight-binding calculations, we investigate the effects of uniaxial strain on the electronic bandstructure of twisted graphene bilayer. We find that the bandstructure is dramatically deformed and the degeneracy of the bands is broken
Dollfus, Philippe, Nguyen, Viet Hung
core +1 more source
Strain-engineered Majorana Zero Energy Modes and {\phi}0 Josephson State in Black Phosphorus [PDF]
, 2018 We develop a theory for strain control of Majorana zero energy modes and Josephson effect in black phosphorus (BP) devices proximity coupled to a superconductor.
Alidoust, Mohammad +2 more
core +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
A theory of the strain-dependent critical field in Nb3Sn, based on anharmonic phonon generation
, 2013 We propose a theory to explain the strain dependence of the critical properties in A15 superconductors. Starting from the strong-coupling formula for the critical temperature, and assuming that the strain sensitivity stems mostly from the electron-phonon
Berthod, Christophe +3 more
core +2 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Meitian dizhi yu kantanObjectiveIn abandoned mines, the storage zones of free gas are closely associated with overburden fractures in goaves. To accurately estimate free gas resources in abandoned mines, it is necessary to thoroughly investigate the rupture mechanisms of ...
Xuefeng TAO +9 more
doaj +1 more source
Energy method in efficient estimation of elastic buckling critical load of axially loaded three-segment stepped column [PDF]
FME Transactions, 2013 This paper treats the elastic stability of three-segment stepped column that is subjected to axial concentrated compressive forces using the strain energy method.
Zdravković Nebojša +2 more
doaj
Mechanical Behavior of High-Performance Yarns Transversely Loaded by Different Indenters
Fibers, 2018 In this study, we performed off-axis transverse loading experiments to study the stress concentration developed in a high-performance yarn with different indenters.
Boon Him Lim, Jou-Mei Chu, Wayne Chen
doaj +1 more source