Results 91 to 100 of about 550,777 (327)

Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik, Benjamin Barthel, Nanna R. Andersen, Sofie V. Skriver, Alan J. Russell, John Vissing   +5 more
wiley   +1 more source

In-Depth Bicycle Collision Reconstruction: From a Crash Helmet to Brain Injury Evaluation

Bioengineering, 2023
Traumatic brain injury (TBI) is a prevalent injury among cyclists experiencing head collisions. In legal cases, reliable brain injury evaluation can be difficult and controversial as mild injuries cannot be diagnosed with conventional brain imaging ...
Xiancheng Yu, Claire E. Baker, Mike Brown, Mazdak Ghajari   +3 more
doaj   +1 more source

A mechanics theory for the exploration of a high-throughput, sterile 3D $\textit{in vitro}$ traumatic brain injury model [PDF]

arXiv, 2023
Brain injuries resulting from mechanical trauma represent an ongoing global public health issue. Several $\textit{in vitro}$ and $\textit{in vivo}$ models for traumatic brain injury (TBI) continue to be developed for delineating the various complex pathophysiological processes involved in its onset and progression. Developing an $\textit{in vitro}$ TBI
arxiv  

Military Service Roles and ALS Among Veterans: A Matched Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT While military service is an established risk factor for amyotrophic lateral sclerosis (ALS), it remains unclear whether this association is linked to combat. We conducted a matched case–control study comparing 191 ALS patients who were veterans of the Israeli Defense Forces (IDF) with known military service type and 1910 matched controls. The
Asaf Honig, Roy Dayan, Amir Knaani, Hagai Levine, Marc Gotkine   +4 more
wiley   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Quantifying Regional Lung Deformation Using Four-Dimensional Computed Tomography: A Comparison of Conventional and Oscillatory Ventilation

Frontiers in Physiology, 2020
Mechanical ventilation strategies that reduce the heterogeneity of regional lung stress and strain may reduce the risk of ventilator-induced lung injury (VILI). In this study, we used registration of four-dimensional computed tomographic (4DCT) images to
Jacob Herrmann, Jacob Herrmann, Jacob Herrmann, Sarah E. Gerard, Wei Shao, Monica L. Hawley, Joseph M. Reinhardt, Joseph M. Reinhardt, Gary E. Christensen, Gary E. Christensen, Eric A. Hoffman, Eric A. Hoffman, Eric A. Hoffman, David W. Kaczka, David W. Kaczka, David W. Kaczka, David W. Kaczka   +16 more
doaj   +1 more source

Multi-directional dynamic model for traumatic brain injury detection [PDF]

arXiv, 2018
Traumatic brain injury (TBI) is a complex injury that is hard to predict and diagnose, with many studies focused on associating head kinematics to brain injury risk. Recently, there has been a push towards using computationally expensive finite element (FE) models of the brain to create tissue deformation metrics of brain injury. Here, we developed a 3
arxiv  

Hamstring strain injury : rate of torque development and previous hamstring strain injury [PDF]

, 2019
Hamstring strain injuries (HSI) are extremely common in football and are the primary cause of re-injury in football players. Although the isokinetic strength ratios have often been used to predict hamstring injuries in football players, the rate of ...
Correia, Paulo Jorge Freitas
core  

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

New Mechanics of Traumatic Brain Injury

, 2008
The prediction and prevention of traumatic brain injury is a very important aspect of preventive medical science. This paper proposes a new coupled loading-rate hypothesis for the traumatic brain injury (TBI), which states that the main cause of the TBI ...
A Kadic, A Pena, A Singh, AA Sabet, AC Eringen, B Morrison, CS Chu, CW Hoge, DC Viano, DC Viano, DGB Edelen, DR Wolfson, DW Brands, E Cosserat, E Cosserat, E Gutierrez, F Loth, G Jian, G Krabbel, GH Bledsoe, H Lamb, H Mao, H Zou, HC Park, HM Huang, J Li, J Park, J Zhang, JA Newman, JC Misra, JC Misra, JFC Yang, JFC Yang, JG Beckwith, K Voo, L Sokoloff, L Zhang, L Zhang, M Hrapko, M Runnerstam, MC LaPlaca, N Yoganandan, NE Leonard, PE Rapp, PV Bayly, RD Mindlin, RS Lakes, S Roth, SE Maier, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, Vladimir G. Ivancevic, W Goldsmith, W Goldsmith, W Yang, Y Guan, Z Chen, Z Zong   +67 more
core   +2 more sources