Results 111 to 120 of about 754,388 (315)

Human umbilical cord blood stem cells and brain-derived neurotrophic factor for optic nerve injury: a biomechanical evaluation

Neural Regeneration Research, 2015
Treatment for optic nerve injury by brain-derived neurotrophic factor or the transplantation of human umbilical cord blood stem cells has gained progress, but analysis by biomechanical indicators is rare.
Zhong-jun Zhang, Ya-jun Li, Xiao-guang Liu, Feng-xiao Huang, Tie-jun Liu, Dong-mei Jiang, Xue-man Lv, Min Luo   +7 more
doaj   +1 more source

Microstructural Evolution and Mechanical Performance of Plasma‐Assisted Hybrid Friction Stir Welded Dissimilar Aluminum–Copper Joints

Advanced Engineering Materials, EarlyView.
Plasma‐assisted hybrid friction stir welding of dissimilar AlCu joints employs localized plasma preheating to balance heat input and enhance plastic flow. The optimized process reduces axial force by up to 35%, refines the microstructure, and achieves ≈96% joint efficiency.
Deepak Kumar Yaduwanshi, Pankaj Shrivastava, Ganesh Chouhan, Velaphi Msomi   +3 more
wiley   +1 more source

Using muscle-tendon load limits to assess unphysiological musculoskeletal model deformation and Hill-type muscle parameter choice.

PLoS ONE
Musculoskeletal simulations are a useful tool for improving our understanding of the human body. However, the physiological validity of predicted kinematics and forces is highly dependent upon the correct calibration of muscle parameters and the ...
Lennart V Nölle, Isabell Wochner, Maria Hammer, Syn Schmitt   +3 more
doaj   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Identifying the Ergonomic Risk Factors of a Job [PDF]

, 2019
[Excerpt] When we experience overexertion of muscles and joints, common symptoms include soreness, pain, discomfort, redness and swelling, limited range of motion, stiffness in joints, weakness and clumsiness, numbing/ tingling sensations (“pins and ...
Brown, Nellie J
core   +1 more source

Sex variation in patellar tendon kinetics during running [PDF]

, 2015
Purpose. The aim of the current investigation was to determine whether female recreational runners exhibit distinct patellar tendon loading patterns in relation to their male counterparts. Methods.
Almekinders, Cappozzo, Cavanagh, Ferber, Ferretti, Greenhalgh, Herzog, Janssen, Johnson, Jonathan Sinclair, Maganaris, McLean, Paul John Taylor, Pearson, Robinson, Sigward, Sinclair, Sinclair, Sinclair, Sinclair, Sinclair, Taunton, Van Gent, Wen   +23 more
core   +2 more sources

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model. [PDF]

, 2019
Introduction:Treatment of open fractures routinely involves multiple surgeries and delayed definitive fracture fixation because of concern for infection.
Bernthal, NM, Hegde, V, Loftin, AH, Niska, J, Segura, T, Stavrakis, AI, Weixian, X, Zhu, S   +7 more
core  

A review of recent perspectives on biomechanical risk factors associated with anterior cruciate ligament injury [PDF]

, 2014
There is considerable evidence to support a number of biomechanical risk factors associated with non-contact anterior cruciate ligament (ACL) injury. This paper aimed to review these biomechanical risk factors and highlight future directions relating to ...
Boden B. P., Chappell D. J., Cruz A., Dai B., Donnelly C. J., Ford K. R., Frank B., Gerwyn Hughes, Grasso R., Griffin L. Y., Grood E. S., Hakkinen K., Herzog W., Irvine L. B., Jacobs C. A., Janssen I., Kernozek T. W., Smith B. A., Stojanovic M. D.   +18 more
core   +2 more sources