Results 251 to 260 of about 249,733 (320)

Sex- and Age-Specific Review of Flag Football Injuries in the United States: A 10-Year Analysis of National Injury Data. [PDF]

Sports Health
Locke AR, Koehne NH, Yendluri A, Laurore C, Obana KK, Tiao J, Saltzman BM, Trofa DP, Li X, Parisien RL.   +9 more
europepmc   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

Advanced Science, EarlyView.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang, Xudan Dou, Yongzhan Sun, Mengyao Wang, Jing Wang, Xinyi Cao, Haijie Xie, Linguo Xie, Weiping Tian, Jing Nie, Yupeng Chen, Chunyu Liu, Lirong Zhang   +12 more
wiley   +1 more source

Effect of neuromeningeal mobilization and postural re-education exercises for persistent hamstring strain: a case report. [PDF]

J Med Case Rep
Kandakurti PK, Muthukrishnan R, Arulsingh W, Hazari A.   +3 more
europepmc   +1 more source

Orally Administered Functional Polyphenol‐Nanozyme‐Armored Probiotics for Enhanced Amelioration of Intestinal Inflammation and Microbiota Dysbiosis

Advanced Science, EarlyView.
This study presents a novel polyphenol‐nanozyme‐armored probiotic system (ECA@EcN) for enhanced treatment of inflammatory bowel disease (IBD). By integrating chitosan‐modified epigallocatechin gallate (EGCG‐CS) with gold nanozymes, the system effectively scavenges ROS, improves probiotic viability, and restores gut microbiota balance.
Yong Zhu, Ziqu Fang, Jie Bai, Longhui Wang, Jiaqing Chen, Zehua Zhang, Qiang Wang, Weiwei Sheng, Xueyin Pan, Zhenyuan Gao, Dengqiu Xu, Pengkai Wu, Beicheng Sun   +12 more
wiley   +1 more source

Sex and Strain-Specific Variations in Motor Recovery Following Compression Spinal Cord Injury: Comparison of Sprague-Dawley and Wistar Rats. [PDF]

Brain Sci
Mojarad N, Doyle D, Garmo LG, Graff R, Reed K, Wolbert PA, Uprety A, Stewart B, Rossignol J, Dunbar GL.   +9 more
europepmc   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Screening and Identification of Novel DNA Aptamer for Targeted Delivery to Injured Podocytes in Glomerular Diseases

Advanced Science, EarlyView.
This study develops RLS‐2, a high‐affinity aptamer that specifically targets injured podocytes, making it a promising candidate for targeted drug delivery. In vitro, RLS‐2 shows stability, specificity, efficient siRNA delivery via AsiCs, and uptake by podocytes.
Chao Zhou, Zhaofeng Luo, Zheng Zhang, Qing Ye, Dongjie Wang, Hanyan Meng, Jiayu Zhang, Shifan Zhu, Lidan Hu, Jianhua Mao   +9 more
wiley   +1 more source

Computational Modelling of Protected and Unprotected Head Impacts in Rugby. [PDF]

Bioengineering (Basel)
Hodges T, Jones A, Del Olmo LP, Mishra A, Caulfield B, Kechadi T, MacManus D, Gilchrist MD.   +7 more
europepmc   +1 more source

ROS‐Activated Nanohydrogel Scaffolds with Multi‐Factors Controlled Release for Targeted Dual‐Lineage Repair of Osteochondral Defects

Advanced Science, EarlyView.
ROS‐activated nanohydrogels composite bilayer scaffolds are rationally designed for targted dual‐lineage repair of osteochondral defects. The as‐prepared nanohydrogel scaffolds provided 3D culture and induced dual‐lineage differentiation of BMSCs in vitro, efficiently inhibited early‐stage inflammation by rapidly releasing DS and improved cartilage and
Xiuhui Wang, Shunli Wu, Ruiyang Li, Huijian Yang, Yue Sun, Zijie Cao, Xiao Chen, Yan Hu, Hao Zhang, Zhen Geng, Long Bai, Zhongmin Shi, Ke Xu, Hongbo Tan, Jiacan Su   +14 more
wiley   +1 more source