Results 51 to 60 of about 739,613 (315)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Parametric analysis of craniocerebral injury mechanism in pedestrian traffic accidents based on finite element methods

Chinese Journal of Traumatology
Purpose: The toughest challenge in pedestrian traffic accident identification lies in ascertaining injury manners. This study aimed to systematically simulate and parameterize 3 types of craniocerebral injury including impact injury, fall injury, and run-
Jin-Ming Wang, Zheng-Dong Li, Chang-Sheng Cai, Ying Fan, Xin-Biao Liao, Fu Zhang, Jian-Hua Zhang, Dong-Hua Zou   +7 more
doaj   +1 more source

Risk Factors Involved in Cheerleading Injuries [PDF]

, 2016
Injury prevention is an important aspect of health in which professionals in the field must focus. With a continual increase of risk in activities performed nationwide, health professionals must seek to educate the population on risk factors involved in ...
DeFreece, Kelsey
core   +2 more sources

New Mechanics of Traumatic Brain Injury

, 2008
The prediction and prevention of traumatic brain injury is a very important aspect of preventive medical science. This paper proposes a new coupled loading-rate hypothesis for the traumatic brain injury (TBI), which states that the main cause of the TBI ...
A Kadic, A Pena, A Singh, AA Sabet, AC Eringen, B Morrison, CS Chu, CW Hoge, DC Viano, DC Viano, DGB Edelen, DR Wolfson, DW Brands, E Cosserat, E Cosserat, E Gutierrez, F Loth, G Jian, G Krabbel, GH Bledsoe, H Lamb, H Mao, H Zou, HC Park, HM Huang, J Li, J Park, J Zhang, JA Newman, JC Misra, JC Misra, JFC Yang, JFC Yang, JG Beckwith, K Voo, L Sokoloff, L Zhang, L Zhang, M Hrapko, M Runnerstam, MC LaPlaca, N Yoganandan, NE Leonard, PE Rapp, PV Bayly, RD Mindlin, RS Lakes, S Roth, SE Maier, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, Vladimir G. Ivancevic, W Goldsmith, W Goldsmith, W Yang, Y Guan, Z Chen, Z Zong   +67 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

White matter changes and confrontation naming in retired aging national football league athletes [PDF]

, 2017
Using diffusion tensor imaging (DTI), we assessed the relationship of white matter integrity and performance on the Boston Naming Test (BNT) in a group of retired professional football players and a control group.
Bartz, Elizabeth K, Conover, Heather, Cullum, C. Munro, Didehbani, Nyaz, Fields, Lindy M, Hart, John, Jr, Jeroudi, Myrtle K, Kraut, Michael A, Mansinghani, Sethesh, Rao, Neena K, Spence, Jeffrey, Strain, Jeremy F, Womack, Kyle B   +12 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Uniaxial stretch-induced axonal injury thresholds for axonal dysfunction and disruption and strain rate effects on thresholds for mouse neuronal stem cells

Journal of Biomechanical Science and Engineering, 2017
In this paper, the proposed study aims to achieve a better understanding of neuronal tolerance and contribute to the prediction of the secondary degeneration of diffuse axonal injury (DAI). Therefore, a uniaxial stretching device which subjected cultured
Evrim KURTOGLU, Hiromichi NAKADATE, Kazuhiro KIKUTA, Shigeru AOMURA, Akira KAKUTA   +4 more
doaj   +1 more source

Evaluation of Head Injury Criteria for Injury Prediction Effectiveness: Computational Reconstruction of Real-World Vulnerable Road User Impact Accidents

Frontiers in Bioengineering and Biotechnology, 2021
This study evaluates the effectiveness of various widely used head injury criteria (HICs) in predicting vulnerable road user (VRU) head injuries due to road traffic accidents.
Fang Wang, Zhen Wang, Lin Hu, Hongzhen Xu, Chao Yu, Fan Li   +5 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source