Results 71 to 80 of about 754,388 (315)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Utilizing a Structural Mechanics Approach to Assess the Primary Effects of Injury Loads Onto the Axon and Its Components

Frontiers in Neurology, 2018
Diffuse axonal injury (DAI) occurs as a result of the transmission of rapid dynamic loads from the head to the brain and specifically to its neurons. Despite being one of the most common and most deleterious types of traumatic brain injury (TBI), the ...
Annaclaudia Montanino, Svein Kleiven
doaj   +1 more source

Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. [PDF]

, 2018
Injectable hydrogels with tunable physiochemical and biological properties are potential tools for improving neural stem/progenitor cell (NSPC) transplantation to treat central nervous system (CNS) injury and disease.
Czechanski, A, Deming, TJ, Kim, JH, O'Shea, TM, Reinholdt, LG, Sofroniew, MV, Wollenberg, AL   +6 more
core   +1 more source

A finite rotation, small strain 2D elastic head model, with applications in mild traumatic brain injury [PDF]

, 2023
Yang Wan, Wenqiang Fang, Rika Wright Carlsen, Haneesh Kesari   +3 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Relationship between anatomical injury site of rectus femoris muscle strain and time taken to return to play in Japanese professional soccer players

Journal of Orthopaedic Surgery, 2022
Purpose The rectus femoris has three myotendinous or myoaponeurosis junctions and causes three types of muscle strain anatomically. We aimed to investigate the anatomical injury site of the rectus femoris muscle strain in professional soccer players as ...
Kengo Shimozaki, Junsuke Nakase, Kazuki Asai, Rikuto Yoshimizu, Mitsuhiro Kimura, Tomoyuki Kanayama, Yusuke Yanatori, Hiroyuki Tsuchiya   +7 more
doaj   +1 more source

Stiffening of the gluteal muscle increased the intramuscular stress: An in-silico implication of deep tissue injury

Heliyon, 2023
Objectives: Deep tissue injury is a common form of pressure ulcers in muscle tissues under bony prominences caused by sustained pressure or shear, which has a great impact on patients with restricted mobility such as spinal cord injury.
Jingyi Jia, Shengbo Gong, Aili Zhang, Liping Jiang, Yifei Yao   +4 more
doaj   +1 more source

Comparative Response of Two Hydrilla Strains to Fluridone [PDF]

, 2005
Experiments were conducted in a controlled-environmental growth chamber to evaluate the response of two strains of the invasive submersed plant Hydrilla verticillata (L.f.) Royle to fluridone (1-methyl-3-phenyl-5-[3-trifluoromethyl)phenyl]- 4(1H ...
Getsinger, K. D., Poovey, Angela G., Stewart, A.B.   +2 more
core  

New Mechanics of Traumatic Brain Injury

, 2008
The prediction and prevention of traumatic brain injury is a very important aspect of preventive medical science. This paper proposes a new coupled loading-rate hypothesis for the traumatic brain injury (TBI), which states that the main cause of the TBI ...
A Kadic, A Pena, A Singh, AA Sabet, AC Eringen, B Morrison, CS Chu, CW Hoge, DC Viano, DC Viano, DGB Edelen, DR Wolfson, DW Brands, E Cosserat, E Cosserat, E Gutierrez, F Loth, G Jian, G Krabbel, GH Bledsoe, H Lamb, H Mao, H Zou, HC Park, HM Huang, J Li, J Park, J Zhang, JA Newman, JC Misra, JC Misra, JFC Yang, JFC Yang, JG Beckwith, K Voo, L Sokoloff, L Zhang, L Zhang, M Hrapko, M Runnerstam, MC LaPlaca, N Yoganandan, NE Leonard, PE Rapp, PV Bayly, RD Mindlin, RS Lakes, S Roth, SE Maier, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, V Ivancevic, Vladimir G. Ivancevic, W Goldsmith, W Goldsmith, W Yang, Y Guan, Z Chen, Z Zong   +67 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source