Results 71 to 80 of about 542,154 (329)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Uniaxial stretch-induced axonal injury thresholds for axonal dysfunction and disruption and strain rate effects on thresholds for mouse neuronal stem cells

Journal of Biomechanical Science and Engineering, 2017
In this paper, the proposed study aims to achieve a better understanding of neuronal tolerance and contribute to the prediction of the secondary degeneration of diffuse axonal injury (DAI). Therefore, a uniaxial stretching device which subjected cultured
Evrim KURTOGLU, Hiromichi NAKADATE, Kazuhiro KIKUTA, Shigeru AOMURA, Akira KAKUTA   +4 more
doaj   +1 more source

A four-season prospective study of muscle strain reoccurrences in a professional football club [PDF]

, 2011
The aim of this investigation was to characterise muscle strain reinjuries and examine their impact on playing resources in a professional football club.
Christopher Carling, Dadebo B., Ekstrand J., Emmanuel Orhant, Engebretsen A. H., Franck Le Gall, Goldman E. F., Mason D. L., Parry L., Petersen J.   +9 more
core   +1 more source

Identification of miRNA signatures associated with radiation-induced late lung injury in mice. [PDF]

, 2020
Acute radiation exposure of the thorax can lead to late serious, and even life-threatening, pulmonary and cardiac damage. Sporadic in nature, late complications tend to be difficult to predict, which prompted this investigation into identifying non ...
Iwamoto, Keisuke S, Lee, Jason T, Lukaszewicz, Agnes I, McBride, William H, Menon, Naresh, Micewicz, Ewa D, Miller, Thomas A, Nguyen, Christine, Olafsen, Tove, Ratikan, Josephine A, Rogers, Claude J, Schaue, Dörthe, Starbird, Mark A, Yamada-Hanff, Jason   +13 more
core   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Predicting Ulnar Collateral Ligament Injury in Rookie Major League Baseball Pitchers [PDF]

arXiv, 2022
In the growing world of machine learning and data analytics, scholars are finding new and innovative ways to solve real-world problems. One solution comes by way of an intersection between healthcare, sports statistics, and data sciences. Within the realm of Major League Baseball (MLB), pitchers are regarded as the most important roster position.
arxiv  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

A Generic Trauma Severity Computer Method Applied to Pedestrian Collisions [PDF]

arXiv, 2020
In the real world, the severity of traumatic injuries are measured using the Abbreviated Injury Scale (AIS). However the AIS scale cannot currently be computed by using finite element human computer models, which calculate a maximum principal strains (MPS). Further, MPS only establishes a threshold above which a serious or fatal injury occurs. In order
arxiv  

A modified controlled cortical impact technique to model mild traumatic brain injury mechanics in mice.

Frontiers in Neurology, 2014
For the past 25 years, controlled cortical impact (CCI) has been a useful tool in traumatic brain injury (TBI) research, creating injury patterns that include primary contusion, neuronal loss, and traumatic axonal damage.
YungChia eChen, Haojie eMao, King H Yang, Ted eAbel, David F Meaney   +4 more
doaj   +1 more source

In-Depth Bicycle Collision Reconstruction: From a Crash Helmet to Brain Injury Evaluation

Bioengineering, 2023
Traumatic brain injury (TBI) is a prevalent injury among cyclists experiencing head collisions. In legal cases, reliable brain injury evaluation can be difficult and controversial as mild injuries cannot be diagnosed with conventional brain imaging ...
Xiancheng Yu, Claire E. Baker, Mike Brown, Mazdak Ghajari   +3 more
doaj   +1 more source