Results 81 to 90 of about 4,424,403 (369)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Utilizing a Structural Mechanics Approach to Assess the Primary Effects of Injury Loads Onto the Axon and Its Components

Frontiers in Neurology, 2018
Diffuse axonal injury (DAI) occurs as a result of the transmission of rapid dynamic loads from the head to the brain and specifically to its neurons. Despite being one of the most common and most deleterious types of traumatic brain injury (TBI), the ...
Annaclaudia Montanino, Svein Kleiven
doaj   +1 more source

Static stretching of the hamstring muscle for injury prevention in football codes: a systematic review [PDF]

, 2012
Purpose: Hamstring injuries are common among football players. There is still disagreement regarding prevention. The aim of this review is to determine whether static stretching reduces hamstring injuries in football codes.
Arnason A, Askling C, Bandy WD, Beaulieu J, Bennell K, Bixler B, Brooks JH, Canale ST, Chumanov ES, Cross KM, Dadebo B, de Bie R, Ekstrand J, Engebretsen AH, Faude O, Faude O, Frigo C, Garrett WE, Hagel B, Heiderscheit BC, Klee A, Liberati A, Mann R, McHugh MP, Moher D, Montgomery WH, Müller-Wolfahrt HW, Orchard J, Orchard J, Orchard J, Orchard J, Orchard JW, Page P, Pope RP, Sackett D, Safran MR, Shellock FG, Shrier I, Smith CA, Stanton P, Thelen DG, van Mechelen W, Verrall GM, Weldon SM, Wiemann K, Wilkinson A, Woods C, Woods C, Yeung EW, Yu B   +49 more
core   +2 more sources

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source

In-Depth Bicycle Collision Reconstruction: From a Crash Helmet to Brain Injury Evaluation

Bioengineering, 2023
Traumatic brain injury (TBI) is a prevalent injury among cyclists experiencing head collisions. In legal cases, reliable brain injury evaluation can be difficult and controversial as mild injuries cannot be diagnosed with conventional brain imaging ...
Xiancheng Yu, Claire E. Baker, Mike Brown, Mazdak Ghajari   +3 more
doaj   +1 more source

An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain

Biomechanics and Modeling in Mechanobiology, 2020
Finite element head (FE) models are important numerical tools to study head injuries and develop protection systems. The generation of anatomically accurate and subject-specific head models with conforming hexahedral meshes remains a significant ...
Xiaogai Li, Zhou Zhou, S. Kleiven
semanticscholar   +1 more source

A Novel Approach to Produce Metal–Metal Composites by Leveraging Immiscibility: Laser Powder Bed Fusion of Nanosilver‐Dispersed Titanium

Advanced Engineering Materials, EarlyView.
Incorporating nanosized silver into titanium for antimicrobial materials exploits the metastable miscibility gap between silver and titanium. Silver nanoparticles are synthesized via pulsed laser ablation in liquid. Silver addition refines the microstructure, increases hardness by 30%, and reduces Staphylococcus capitis microbial adhesion by 70%, with ...
Hamed Shokri, Silja‐Katharina Rittinghaus, Janett Schmelzer, Jessica Bertrand, Bilal Gökce   +4 more
wiley   +1 more source

TLR4 signaling is essential for survival in acute lung injury induced by virulent Pseudomonas aeruginosa secreting type III secretory toxins

Respiratory Research, 2004
Background The relative contributions of the cytotoxic phenotype of P. aeruginosa expressing type III secretory toxins and an immunocompromised condition lacking normal Toll-like receptor 4 (TLR4) signaling in the pathogenesis of acute lung injury and ...
Moriyama Kiyoshi, Fujimoto Junichi, Ajayi Temitayo, Sawa Teiji, Faure Karine, Shime Nobuaki, Wiener-Kronish Jeanine P   +6 more
doaj   +1 more source

The potential of Antheraea pernyi silk for spinal cord repair [PDF]

, 2017
This work was supported by the Institute of Medical Sciences of the University of Aberdeen, Scottish Rugby Union and RS McDonald Charitable Trust. We are grateful to Mr Nicholas Hawkins from Oxford University and Ms Annette Raffan from the University of ...
Huang, W, Knight, D, Lesage, S, Rajnicek, A M, Varone, A, Vollrath, F   +5 more
core   +2 more sources

3D‐Printed Architected Material for the Generation of Foam‐Based Protective Equipment

Advanced Engineering Materials, EarlyView.
This study investigates 3D‐printed architected structures as alternatives to traditional foams in protective gear. It focuses on customizing impact strength and damping through design and manufacturing integration. Testing shows these structures outperform conventional foams, offering enhanced customizability, lower weight, and tunable performance ...
Ali Zolfagharian, Gerard Bel Català, Daniel Saakes, Bernard Rolfe, Ian Gibson, Mehrshad Mehrpouya   +5 more
wiley   +1 more source