Results 101 to 110 of about 9,117,404 (329)

Review of Trackside Monitoring Solutions: From Strain Gages to Optical Fibre Sensors

open access: yesSensors, 2015
A review of recent research on structural monitoring in railway industry is proposed in this paper, with a special focus on stress-based solutions. After a brief analysis of the mechanical behaviour of ballasted railway tracks, an overview of the most ...
Georges Kouroussis   +5 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

A Review of Surface Deformation and Strain Measurement Using Two-Dimensional Digital Image Correlation

open access: yes, 2016
Among the full-field optical measurement methods, the Digital Image Correlation (DIC) is one of the techniques which has been given particular attention. Technically, the DIC technique refers to a non-contact strain measurement method that mathematically
Sze-Wei Khoo   +2 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Advanced video extensometer for non-contact, real-time, high-accuracy strain measurement.

open access: yesOptics Express, 2016
We developed an advanced video extensometer for non-contact, real-time, high-accuracy strain measurement in material testing. In the established video extensometer, a "near perfect and ultra-stable" imaging system, combining the idea of active imaging ...
B. Pan, Long Tian
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Determination of the State of Strain of Large Floating Covers Using Unmanned Aerial Vehicle (UAV) Aided Photogrammetry

open access: yesSensors, 2017
Floating covers used in waste water treatment plants are one of the many structures formed with membrane materials. These structures are usually large and can spread over an area measuring 470 m × 170 m.
Wern Hann Ong   +3 more
doaj   +1 more source

Effect of picosecond strain pulses on thin layers of the ferromagnetic semiconductor (Ga,Mn)(As,P)

open access: yes, 2010
The effect of picosecond acoustic strain pulses (ps-ASP) on a thin layer of (Ga,Mn)As co-doped with phosphorus was probed using magneto-optical Kerr effect (MOKE).
A. Lemaître   +9 more
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Evaluation of Bending Deformations in Slender Cylindrical Structures Using Distributed Optical Fibre Strain Sensing

open access: yesSensors
Structures with slender cylindrical geometries, such as subsea power cables are critical components of infrastructure systems. These structures are prone to bending deformation under load, which can ultimately cause structural failure.
Madhubhashitha Herath   +3 more
doaj   +1 more source

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