Results 111 to 120 of about 9,117,404 (329)

Synthetic Spectrum Approach for Brillouin Optical Time-Domain Reflectometry

open access: yesSensors, 2014
We propose a novel method to improve the spatial resolution of Brillouin optical time-domain reflectometry (BOTDR), referred to as synthetic BOTDR (S-BOTDR), and experimentally verify the resolution improvements.
Ken'ichi Nishiguchi   +3 more
doaj   +1 more source

Design and commission of an experimental test rig to apply a full-scale pressure load on composite sandwich panels representative of aircraft secondary structure

open access: yes, 2010
This paper describes the design of a test rig, which is used to apply a representative pressure load to a full-scale composite sandwich secondary aircraft structure.
Crump, D.A.   +2 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

A Circular Microstrip Antenna Sensor for Direction Sensitive Strain Evaluation

open access: yesSensors, 2018
In this paper, a circular microstrip antenna for stress evaluation is studied. This kind of microstrip sensor can be utilized in structural health monitoring systems. Reflection coefficient S11 is measured to determine deformation/strain value.
Przemyslaw Lopato, Michal Herbko
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Strain measurement using oscillator circuit sensor with high sampling frequency

open access: yesNihon Kikai Gakkai ronbunshu, 2019
A strain measurement system based on astable multivibrator using CMOS inverter has been developed. This system could omit an amplifier, filter and A/D converter unlike conventional Wheatstone bridge type sensor, because strain is measured by counting ...
Shumpo KITAMURA   +3 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Design of auto-calibration system for multi-channel strain gauge

open access: yesGong-kuang zidonghua, 2016
In view of problem of wasting time and energy and low efficiency in calibrating process of existing calibration method of strain gauges which adopts single-channel manual operation mode, an auto-calibration system based on cortex-M3 MCU was designed ...
XU Lijiao, LIU Xiang, JI Xiaoju
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

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