Results 71 to 80 of about 382,947 (255)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Effects of boundary condition and cell structure on dynamic axial crushing honeycomb

Mechanical Engineering Journal, 2018
The dynamic axially crushing behavior of metal honeycombs was studied with placing emphasis on the effects of boundary condition and cell structure on its characteristics as an energy absorber. Numerical honeycomb models of some metal foil materials were
Tsutomu UMEDA, Koji MIMURA
doaj   +1 more source

Frequency Domain Simulations of Charge-Density-Wave Strains: Comparison with Electro-Optic Measurements

, 2007
We have studied changes in charge-density-wave strain under application of square-wave currents of variable amplitude and frequency by numerically solving the phase-slip augmented diffusion model introduced by Adelman et al (Phys. Rev. B 53, 1833 (1996)).
Adelman, Brazovskii, Gill, Grüner, Itkis, Itkis, J.W. Brill, L. Ladino, Ladino, Ladino, Lee, Lemay, Littlewood, Ogawa, Ramakrishna, Schlenker, Wong, Zaitsev-Zotov   +17 more
core   +1 more source

Quenched disorder induced magnetization jumps in (Sm,Sr)MnO$_3$ [PDF]

, 2004
Magnetic field induced step-like changes in magnetization and resistivity of SmSr manganites were studied. A strong dependence of these features on the cooling rate was observed.
A. Aliev, A. V. Kalinov, C. Martin, D. I. Khomskii, H. Yoshizawa, I. F. Voloshin, J. Kushauer, L. M. Fisher, N. A. Babushkina, T. T. M. Palstra, Y. Tomioka, Y. Zhang   +11 more
core   +4 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Study of Uniaxial Tensile Properties of Hexagonal Boron Nitride Nanoribbons

, 2017
Uniaxial tensile properties of hexagonal boron nitride nanoribbons and dependence of these properties on temperature, strain rate, and the inclusion of vacancy defects have been explored with molecular dynamics simulations using Tersoff potential.
Dhar, Rajkumar, Mojumder, Satyajit, Motalab, Mohammad Abdul, Paul, Ratul, Saha, Sourav, Tasnim, Tamanna   +5 more
core   +1 more source

One-dimensional modeling of necking in rate-dependent materials [PDF]

, 2019
This paper presents an asymptotically rigorous one-dimensional analytical formulation capable of accurately capturing the stress and strain distributions that develop within the evolving neck of bars and sheets of rate-dependent materials stretched in ...
Audoly, Basile, Hutchinson, John W.
core   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Effect of high strain rate on micro-indentation test in pure aluminum

EPJ Web of Conferences, 2012
The indentation properties of pure aluminum (99.9%, 3N aluminum) and high purity aluminum (99.999%, 5N aluminum) with respect to the strain rate dependence of strength are experimentally investigated in order to clarify the effect of strain rate on the ...
Kobayashi H., Horikawa H., Shimizu Y., Ogasawara N., Yamada H.   +4 more
doaj   +1 more source