Results 71 to 80 of about 4,698,964 (243)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Sonoelastography Findings in Breast Cancer: Correlation with Molecular Subtypes and Ki-67 Expression

Indonesian Journal of Cancer
Background: Strain elastography is increasingly used as a complementary imaging tool to assess suspicious breast lesions by evaluating tissue stiffness using the strain ratio and elastography score. Owing to the intertumor heterogeneity of breast cancer,
Lydia Purna Kuntjoro, Ignatius Riwanto, Hermina Sukmaningtyas, Yan Wisnu Prajoko, Suhartono Suhartono, Lina Choridah, Endang Mahati, Clarissa Aulia Pravitha   +7 more
doaj   +1 more source

Additional value of qualitative strain ultrasound elastography and strain ratio in predicting thyroid malignancy

The Egyptian Journal of Radiology and Nuclear Medicine, 2017
Objective: To detect if strain ultrasound elastography and strain ratio have additional value to the conventional grey scale ultrasound in predicting thyroid malignancy.
Mai E.M. Khamis, Ahmad Abdel Azim Ismail, Ahmed M. Alaa El-deen, Mohamed Farouk Amin   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Modeling Uncertainty of Strain Ratio Measurements in Ultrasound Breast Strain Elastography: A Factorial Experiment

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2020
Strain elastography (SE) is a technique in which images of localized tissue strains are used to detect the relative stiffness of tissues. The application of SE in differentiating malignant breast lesions from benign ones has been broadly investigated. The strain ratio (SR) between the background and the breast tumor has been used and its results have ...
David Rosen, Jingfeng Jiang
openaire   +3 more sources

Diagnostic Value of Elastography, Strain Ratio, and Elasticity to B-Mode Ratio and Color Doppler Ultrasonography in Breast Lesions

International Journal of General Medicine, 2020
Mahnaz Ranjkesh,1,2 Farid Hajibonabi,2– 4 Fatemeh Seifar,5 Mohammad Kazem Tarzamni,1,2 Behzad Moradi,1,2 Zhila Khamnian6 1Medical Radiation Sciences Research Group, Tabriz University of Medical Sciences, Tabriz, Iran; 2Radiology Department, Tabriz ...
Ranjkesh M, Hajibonabi F, Seifar F, Tarzamni MK, Moradi B, Khamnian Z   +5 more
doaj  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Ultrasound Elastography and Strain Ratio Evaluation of Breast Masses

International Journal of Anatomy Radiology and Surgery, 2018
Introduction: Breast masses are most commonly encountered problem in the most of the women population out of which breast cancers are the commonest leading malignancies.
Ravi Teja Athkuri, Venu Madhav Muppavarapu, Pooja Reddy Yelmareddy   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source