Results 91 to 100 of about 35,811 (290)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
On the contrast between Germanic and Romance negated quantifiers
Bucharest Working Papers in Linguistics, 2009 Universal quantifiers can be stranded in the manner described by Sportiche (1988), Giusti (1990) and Shlonsky (1991) in both the Romance and Germanic languages, but a negated universal quantifier can only be stranded in the Germanic languages.
Robert Cirillo
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Even though any types of unexpected risks can render stranded assets— stranded resources (beyond financial resources) that cannot be used or developed further— the concept has been increasingly linked to environmental issues, particularly climate change.
openaire +1 more source
Faster magnetic resonance imaging in emergency room patients with right lower quadrant pain and suspected acute appendicitis [PDF]
, 2018 Purpose: Emergency Departments (ED) are becoming busier, with a resultant increase in the number of imaging referrals. The purpose of this study was to assess the diagnostic accuracy of an abbreviated two sequence magnetic resonance (MR) protocol for ...
Ali, Ismail T. +6 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Frontiers in Environmental EconomicsClimate policy will inevitably lead to the stranding of fossil energy assets such as production and transport assets for coal, oil, and natural gas.
Franziska M. Hoffart +3 more
doaj +1 more source
Structural Separation Models and the Provision of ‘Dark Fibre’ for Broadband Networks: The Case of CityLink [PDF]
Fibre broadband networks are widely presumed to become the dominant form of fixed-line broadband access. However, the spectre of fibre firms gaining market power, such has been evidenced in legacy copper-based telecommunications networks, has led some ...
Howell, Bronwyn
core +1 more source
On the Acquisition of Universal and Parameterised Goal Accessibility Constraints by Japanese Learners of English [PDF]
, 2011 This paper reports on how adult Japanese Learners of English/JLEs acquire universal and parameterised constraints which regulate the accessibility of Goals to Wh-Movement, and which determine whether subordinate or superordinate material is pied-piped or
Radford, A, Yokota, H
core