Results 51 to 60 of about 35,811 (290)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Modelling optical fibre cable [PDF]

open access: yes, 1996
Optical fibre cables are made by placing optical fibres inside a loose tube packed with a water based gel, and then winding these loose tubes on to a central strength member in helically wound sections of alternating twist separated by reversing sections.
Fackerell, T., Fraser, B.
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Strands

open access: yesAltre Modernità, 2017
Altre Modernità, 2017: NUMERO SPECIALE: Will forever young!
openaire   +3 more sources

Rescue, rehabilitation, and release of marine mammals: An analysis of current views and practices. [PDF]

open access: yes, 1996
Stranded marine mammals have long attracted public attention. Those that wash up dead are, for all their value to science, seldom seen by the public as more than curiosities.
Geraci, Joseph R.   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

What drives asset and resource stranding in the transition from fossils to clean energy? a systematic review

open access: yesFrontiers in Energy Research
The study investigates the drivers and mechanisms of asset and resource stranding in the context of energy transitions. A systematic review approach was used to analyze existing studies, identify the drivers of energy resource and asset stranding, and ...
Rochelle Gladys Kemitare   +6 more
doaj   +1 more source

LTAG analysis for pied-piping and stranding of wh-phrases [PDF]

open access: yes, 2004
In this paper we propose a syntactic and semantic analysis of complex questions. We consider questions involving pied piping and stranding and we propose elementary trees and semantic representations that allow to account for both constructions in a ...
Kallmeyer, Laura, Scheffler, Tatjana
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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