Results 191 to 200 of about 445,570 (295)

Prognostic relevance and molecular correlates of Claudin-1 expression in pancreatic neuroendocrine tumors. [PDF]

Hum Pathol
Fattori A, Lu X, Baltzinger P, Bachellier P, Addeo P, Imperiale A, Pessaux P, Kurtz JE, Goichot B, Baumert TF, Chenard MP, Malouf GG.   +11 more
europepmc   +1 more source

Interaction with NEGR1 affects mGlu5 cell signalling and the neuroprotection induced by the positive allosteric modulator VU0409551

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The metabotropic glutamate receptor mGlu5 plays an important role in neuronal survival and synaptic plasticity. We and others have shown that mGlu5 positive allosteric modulators (PAMs) are biased agonists, triggering the activation of neuroprotective pathways and promoting neuronal survival. As mGlu5 biased pharmacology
Jennifer D. S. Guimaraes, Toniana G. Carvalho, Luan A. Pereira, Emanuele G. Silva, Esther M. A. Maciel, Gabriella P. Torres, Thiago Assis, Pablo L. Cardozo, Joao P. P. de Almeida, Nathalia C. Silva, Francesca Pischedda, Giovanni Piccoli, Luciene B. Vieira, Juliana Alves‐Silva, Fabiola M. Ribeiro   +14 more
wiley   +1 more source

Treatment interventions for co-occurring opioid use disorder, and sleep disturbances: a scoping review. [PDF]

Subst Abuse Treat Prev Policy
Ruppert E, Rolling J, Medde A, Durpoix A, Lalanne L.   +4 more
europepmc   +1 more source

Dynamic Wave Trains: A Procedural Approach to Spatially Varying Ocean Synthesis

Computer Graphics Forum, EarlyView.
In this paper, we present a high performance procedural model capable of synthesizing and rendering a virtually infinite ocean. Our method exhibits spatial variations as the orientations, speed and choppiness of the waves is parametrized for each frequencies and each point in space. The provided visual abstract exhibits a sunset rendering of a large 40 
Romain Fournier, Arthur Laurain, Pierre Kraemer, Guillaume Gilet, Basile Sauvage   +4 more
wiley   +1 more source

Pleiotropic Phenotype of RYR2 Exon 3 Deletion: Biventricular Noncompaction and Malignant Arrhythmias. [PDF]

JACC Case Rep
Faucher L, Cardi T, Fitouchi S, Baldacini C, Koenig B, Schatz A, Kanso M, Morel O, Marzak H, Jesel L.   +9 more
europepmc   +1 more source

Factors Associated With Patient‐Reported Outcomes More Than 5 Years After Dental Implant Therapy: A Cross‐Sectional Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate patient‐reported outcome (PROs) and their associated factors in patients treated with dental implants more than 5 years earlier. Materials and Methods In this cross‐sectional study, patients with implants (> 5 years) completed a self‐administered questionnaire assessing functional, aesthetic, psychosocial and economic ...
Simone Sbalchiero, Grégoire Habay, Pierre‐Yves Gegout, Olivier Huck   +3 more
wiley   +1 more source

Pierre Chambon, a pioneer of molecular biology and gene regulation in eukaryotes. [PDF]

Proc Natl Acad Sci U S A
Metzger D.
europepmc   +1 more source

Producing a Red List of Ecosystems for the Brazilian Cerrado

Conservation Science and Practice, EarlyView.
Land clearance is a key driver of biodiversity loss. This is a particular issue in the Brazilian Cerrado, the world's most biodiverse savanna biome and a region experiencing the rapid expansion of agriculture. By using the Red List of Ecosystems as an international standard, we provide the first globally comparable analysis of the state of the Cerrado,
Juliana Ávila Martins, Robert J. Smith
wiley   +1 more source

Coupled FE Modeling of Superelastic NiTi Arch Wire and Bone Remodeling to Simulate 3D Orthodontic Tooth Movement During Leveling Phase. [PDF]

Int J Numer Method Biomed Eng
Abou Hamdan M, Wagner D, Jmal H, Touchal S.   +3 more
europepmc   +1 more source

Private money and money market integration: The role of payments infrastructure in nineteenth‐century Switzerland

The Economic History Review, EarlyView.
Abstract Using newly collected discount rate data for six Swiss cities from 1846 to 1893, we find no evidence of increasing integration during a 30‐year period of lightly regulated free banking. We attribute this to two structural issues: banks had incentives to ward off competitors by protecting their local monopolies or forming cartels, and there was
Daniel Kaufmann, Rebecca Stuart
wiley   +1 more source