Results 181 to 190 of about 11,186,117 (295)

Associations between self-management strategies and clinical outcomes in depression: a cross-sectional survey. [PDF]

Front Psychiatry
Tada T, Sakurai H, Maruki T, Murao M, Matsumoto Y, Aoki Y, Tachimori H, Imamura Y, Matsumoto Y, Sawada N, Hongo S, Makino S, Tada K, Tsuboi T, Watanabe K.   +14 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The choice of corporate social responsibility strategies under rivalry: Whether to increase socially responsible product characteristics or enhance relationship with buyers. [PDF]

PLoS One
Zhao X.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Progress in sustainment? Reflections on ongoing gaps and opportunities for the field of implementation science in response to Dopp et al., 2025. [PDF]

Implement Sci
Shelton RC, Sichel CE.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Conversation Barriers and Strategies Used by People With Parkinson's and Their Partners to Support Conversation. [PDF]

Int J Lang Commun Disord
Thilakaratne R, Wylie K, Loftus AM, Cocks N.   +3 more
europepmc   +1 more source

Diagnostic agro-socio-economique de la zone d'intervention du Projet (Districts de Pek, Kham et Nonghet) : Programme national agroécologie (PRONAE), Province de Xieng Khouang [PDF]

, 2004
Dangé, Guillaume, Lienhard, Pascal, Sosomphou, Thammakham, Syphanravong, Somchanh, Talon, Marie Pierre   +4 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A longitudinal psychological model of writing development: interactions among self-efficacy, regulation, and anxiety. [PDF]

Front Psychol
Cheng S, Lin C, Wei D, Chen Y.
europepmc   +1 more source