Results 61 to 70 of about 11,186,117 (295)

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

P-gp quantification for cell resistance studies in leukemia cells using the innovative LightSpot-FL-1 fluorescent conjugate

Scientific Reports
Multidrug resistance proteins contribute to chemotherapy resistance in various cancers. Among them, the P-glycoprotein (P-gp) has been the most investigated.
Maxime Dubois, Antoine Goisnard, Céline Bourgne, Elodie Gay, Marie Depresle, Manon Roux, Allison Voisin, Marc Berger, Frédérique Penault-Llorca, Emmanuelle Mounetou, Pierre Daumar, Mahchid Bamdad   +11 more
doaj   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Early Onset Multiple Primary Tumors in Atypical Presentation of Cowden Syndrome Identified by Whole-Exome-Sequencing

Frontiers in Genetics, 2018
A family with an aggregation of rare early onset multiple primary tumors has been managed in our oncogenetics department: the proband developed four early onset carcinomas between ages 31 and 33 years, including acral melanoma, bilateral clear cell renal
Mathias Cavaillé, Mathias Cavaillé, Flora Ponelle-Chachuat, Flora Ponelle-Chachuat, Nancy Uhrhammer, Nancy Uhrhammer, Sandrine Viala, Sandrine Viala, Mathilde Gay-Bellile, Mathilde Gay-Bellile, Maud Privat, Maud Privat, Yannick Bidet, Yannick Bidet, Yves-Jean Bignon, Yves-Jean Bignon   +15 more
doaj   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Product design and business model strategies for a circular economy

, 2016
The transition within business from a linear to a circular economy brings with it a range of practical challenges for companies. The following question is addressed: What are the product design and business model strategies for companies that want to ...
N. Bocken, I. de Pauw, C. Bakker, Bram van der Grinten   +3 more
semanticscholar   +1 more source

Optimal strategies of hedging portfolio of unit-linked life insurance contracts with minimum death guarantee [PDF]

Dans ce papier, nous nous intéressons à la couverture des contrats en unités de compte avec garanties décès. Nous présentons des stratégies de couverture opérationnelles permettant de réduire de façon significative les coûts futurs liés à ce type de ...
Frédéric Planchet, Oberlain Nteukam Teuguia, Pierre-Emmanuel Thérond   +2 more
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Diaspora, Développement et Citoyenneté: Les Migrants Originaires du Bassin du Fleuve Sénégal [PDF]

, 2005
The author analyses the contribution of the diaspora on the development of their ...
Olivier le Masson, Samba Yatera
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Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Ambiguity in electoral competition. [PDF]

L'article propose une théorie de la compétition électorale ambigüe. Une plate-forme est ambigüe si les votants peuvent l'interpréter de différentes manières.
Jean-François Laslier
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