Results 151 to 160 of about 473,282 (268)

Strategic Decisions and the Entrepreneurial Mindset in Sustaining Agribusiness SMEs in Emerging Economies: Unlocking Pathways to Resilience - A Narrative Review. [PDF]

F1000Res
Nyamboga TO.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Strategic Reform for the Non-Communicable Disease Crisis in Bangladesh: A Narrative Review of Policy Drivers and Systemic Solutions. [PDF]

Health Sci Rep
Mamun AA.
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Divergence among species with "good competitor" and "good cultivator" strategies promotes asymmetric facilitation among co-invaders. [PDF]

Nat Commun
Li CW, Liao HX, Callaway RM, Su ZY, Zou JK, Liu A, Wu YR, Fang YQ, Peng SL, Chen BM.   +9 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

A game-theoretic framework for multimodal information utilization under heterogeneous processing environments in neuroscience and perception science. [PDF]

Front Neurosci
Cui Z, Li K.
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Correction to "Integrating Central Venous and Arterial Line Placement Training for Respiratory Therapists: A Sustainable Strategic Approach to Enhance Patient Care". [PDF]

Crit Care Res Pract
europepmc   +1 more source

Between Eagle and Dragon: Affective representations of the United States and China in South Korean Media. [PDF]

PLoS One
Han S.
europepmc   +1 more source