Results 201 to 210 of about 473,282 (268)

Comparative analysis of strategic vs. computational thinking in management. [PDF]

Front Artif Intell
Nyenno I.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Speed and quality of complex strategic decisions. [PDF]

Proc Natl Acad Sci U S A
Sunde U, Zegners D, Strittmatter A.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

NAPCRG Launches New Strategic Plan. [PDF]

Ann Fam Med
Vansaghi T, Gross N.
europepmc   +1 more source

The Effect of Corporate Governance and Transformational Leadership on Business Strategy and Business Performance Moderated by Government Policy. [PDF]

F1000Res
Willy M, Al Musadieq M, Abdillah Y, Nuzula NF.   +3 more
europepmc   +1 more source

Capability-environment configurations driving exploratory innovation in art entrepreneurs: A mixed-methods configurational study. [PDF]

PLoS One
Chai Z, Yang N.
europepmc   +1 more source

CEO narcissism and its influence on innovation capabilities of micro, small, and medium-sized enterprises: An empirical study in the Colombian context. [PDF]

PLoS One
Parodi Camaño TA, Vidal Durango JV, Portnoy I.   +2 more
europepmc   +1 more source

Progress toward the 2030 targets of Brazil's Strategic Action Plan for noncommunicable diseases: a time-series and projection analysis of risk factors. [PDF]

Lancet Reg Health Am
Wahrhaftig J, Ferrari G, Claro R, Antunes ABS, Cardoso LO, Rezende LFM.   +5 more
europepmc   +1 more source