Results 71 to 80 of about 26,820,360 (304)

Integrated multimodel analysis reveals achievable pathways toward reliable, 100% renewable electricity for Los Angeles

Cell Reports Sustainability
Summary: Climate change has prompted many communities to set targets for carbon-free power supplies, but they often lack data-driven strategies to achieve them.
Jaquelin Cochran, Paul Denholm, Meghan Mooney, Daniel Steinberg, Elaine Hale, Garvin Heath, Bryan Palmintier, David Keyser, Devonie Oleson, Doug Arent, Henry Horsey, Anthony Fontanini, Matteo Muratori, Jennie Jorgenson, Vikram Ravi, Brady Cowiestoll, Ben Sigrin, Kelsey Horowitz, Himanshu Jain, Matt Irish, Scott Nicholson, George Ban-Weiss, Harvey Cutler   +22 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Second-generation downscaled earth system model data using generative machine learningOEDI

Data in Brief
The second-generation Sup3rCC dataset provides high-resolution meteorological data generated through the downscaling of multiple earth system models (ESMs) from the Coupled Model Intercomparison Project Phase 6 (CMIP6).
Grant Buster, Brandon N. Benton, Deeksha Rastogi, Shih-Chieh Kao, Guilherme Castelao, Jordan Eisenman   +5 more
doaj   +1 more source

An Extension of Neutrosophic AHP-SWOT Analysis for Strategic Planning and Decision-Making

Symmetry, 2018
Every organization seeks to set strategies for its development and growth and to do this, it must take into account the factors that affect its success or failure. The most widely used technique in strategic planning is SWOT analysis.
Mohamed Abdel-Basset, M. Mohamed, F. Smarandache   +2 more
semanticscholar   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A comparative fMRI meta‐analysis of altruistic and strategic decisions to give

NeuroImage, 2019
&NA; The decision to share resources is fundamental for cohesive societies. Humans can be motivated to give for many reasons. Some generosity incurs a definite cost, with no extrinsic reward to the act, but instead provides intrinsic satisfaction ...
Jo Cutler, D. Campbell-Meiklejohn
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Rise of the Insumer: A Key Stakeholder of Crowdfunding

Zeszyty Naukowe Uniwersytetu Ekonomicznego w Krakowie
Objective: Crowdfunding is a rapidly growing part of economy, with USD 8,003,935,277 being collected through the Kickstarter.com platform alone as of 11 May 2024.
Oskar Kosch
doaj   +1 more source