Results 71 to 80 of about 23,258,662 (303)

Learning from history: some strategic lessons from the ‘forward defence’ era [PDF]

open access: yes, 2015
This paper assesses the way the government handled commitments to three conflicts in Southeast Asia; the Malayan Emergency, Indonesian Confrontation and the Vietnam War.
Peter Edwards
core  

Second-generation downscaled earth system model data using generative machine learningOEDI

open access: yesData in Brief
The second-generation Sup3rCC dataset provides high-resolution meteorological data generated through the downscaling of multiple earth system models (ESMs) from the Coupled Model Intercomparison Project Phase 6 (CMIP6).
Grant Buster   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Strategic information systems research : an archival analysis [PDF]

open access: yes, 2010
The Journal of Strategic Information Systems (JSIS) has been an international outlet for Information Systems research that focuses on strategic issues since 1991. This paper reports on an analysis of the research published in JSIS to date.
Gable, Guy G.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Indochina 1945

open access: yes, 1945
Provisional editionIncludes glossary and "Reliability of data" table.; "No.
United States. Office of Strategic Services. Research and Analysis Branch   +1 more
core  

Regional Strategic Analysis and Knowledge Support System (ReSAKSS)

open access: yes, 2020
Regional strategic analysis and knowledge support system (ReSAKSS) is a Africa-focused database nodes that compile, analyze, and disseminate data, information, and tools to help design, implement, monitor, and evaluate rural development strategies.Non ...
Regional Strategic Analysis and Knowledge Support System (ReSAKSS)
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Sources of tension in the Asia–Pacific: strategic competition, divided regionalism and non-traditional security challenges [PDF]

open access: yes, 2013
  This the first in a series of three papers commissioned for a project that ASPI has been jointly running with Canada’s Centre for International Governance Innovation (CIGI). The project explores the rationale for and possible mechanisms of closer
James Manicom
core  

Home - About - Disclaimer - Privacy