Results 101 to 110 of about 127,771 (308)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Environmental Structure and Theories of Strategic Choice

open access: yes, 1988
This article argues that the prevailing dichotomization of organizational studies into voluntarist and deterministic orientations is too simple, and that this simplicity has dangerous consequences for accounts of strategic choice.
Whittington, Richard
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Strategic Media, Cynical Public? Examining the Contingent Effects of Strategic News Frames on Political Cynicism in the UK

open access: yes, 2010
Through the use of experimental methods, this study examines the claim that strategic news engenders political cynicism. Firstly, it builds upon previous theory by conceptualising and measuring political cynicism at both issue-specific and global levels.
Jackson, Dan, Dan Jackson
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

DEFINITION OF PERSPECTIVE DIRECTION OF DEVELOPMENT OF SMALL BVUSINESS IN REGION OF RUSSIA [PDF]

open access: yesЭкономика региона, 2008
Problems of strategic planning of small business development in the Russian Federation regions are considered in this article that include ambiguity of strategic directions of small business development, monitoring and control mechanisms of strategic ...
N.M. Filimonova
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Strategic Choice of Domestic Environmental Policy Instrument and International Emissions Trading Scheme in an Open Economy with Imperfect Competition

open access: yes
This paper presents a model of imperfect international competition. Within this framework, the optimal choice of national environmental policy instrument and international emissions trading scheme is discussed.
Boom, Jan Tjeerd
core  

Three essays on strategic aspects in oligopoly with vertical structure

open access: yes, 2013
Kashefi MA. Three essays on strategic aspects in oligopoly with vertical structure. Bielefeld: Bielefeld University; 2013.Thus, what is of supreme importance in war is to attack the enemy's strategy.
Kashefi, Mohammad Ali
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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