Results 71 to 80 of about 127,771 (308)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

From the delisting case of P&G to its strategic adjustments and financial status in recent years [PDF]

open access: yesSHS Web of Conferences
As a giant in the FMCG industry, P&’s every move has influenced the choice of consumers and the trend of the industry. In order to maintain their profitability and competitive position, they attach great importance to strategic management. They had their
Wang Yihong
doaj   +1 more source

The Cognitive Perspective in Strategic Choice

open access: yesSSRN Electronic Journal
This paper examines to what degree organizations use strategies that focus on maximizing shareholder value (Theory E) or if they use strategies emphasizing the development of organizational capability (Theory O). Applying a cognitive perspective in strategic choice, our main goal was to investigate to what extent cognitive biases influenced strategic ...
Kenneth Midtgård, Marcus Selart
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

STRATEGIC MANAGEMENT ACCOUNTING: DEFINITION AND TOOLS

open access: yesAktualʹnì Problemi Rozvitku Ekonomìki Regìonu, 2017
The article is dedicated to learning the essence of the definition of “strategic management accounting” in domestic and foreign literature. Strategic management accounting tools has been studied and identified constraints that affect its choice.
Nadiia Pylypiv, Iryna Pіatnychuk
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

ENTERPRISE RESOURCE STRATEGIC PLANNING: TARGET CHOICE TECHNIQUES

open access: yesМодернизация, инновация, развитие, 2016
Choice of the targets is one of most important elements of the resource planning system. Particular feature of the strategic planning is development of future alternatives for the enterprise.
A. S. Lankin
doaj  

Rethinking AML/CFT risk management: Towards a risk strategy for banks

open access: yesJournal of Economic Criminology
This study conceptualises a risk strategy framework for anti-money laundering and countering the financing of terrorism (AML/CFT) through a theory synthesis approach, integrating contributions from four literature streams into a conceptual framework. The
Sonja Korpela   +2 more
doaj   +1 more source

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