Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
The Relationship between Metacognitive Strategies Awareness and Listening Comprehension of Non-Iranian Advanced Level Persian Language Learners [PDF]
زبان پژوهیOne of the challenges of second language learners is listening comprehension. In this context, Field (2008: 4) says that if we ask many language learners to determine the relative difficulty of the four language skills, many of them consider listening to
Seyed Akbar Jalili, Seyyed Mehdi Abtahi
doaj +1 more source
The Influence of Managerial and Organizational Determinants of Horizontal Knowledge Exchange on Competence Building and Competence Leveraging [PDF]
, 2005 Both in theory as in practice insight is limited about how firms in dynamic environments could organize to manage concurrently both the strategic processes of competence building and competence leveraging.
Bosch, F.A.J. (Frans) van den +2 more
core
A resource-advantage perspective on pricing: shifting the focus from ends to means-end in pricing research? [PDF]
, 2013 This paper contributes to a long-lasting debate between practitioners who argue that academia is unable to understand what pricing is all about and academics who criticize practitioner pricing approaches for lacking rigor or rationality.
Roper, Angela, van der Rest, Jean-Pierre
core +2 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Orientaciones para la inclusión de las estrategias en el programa habitual de ELE [PDF]
marcoELE. Revista de Didáctica Español Lengua Extranjera, 2008 Pese a haberse convertido en uno de los objetivos del currículo, el desarrollo de la competencia estratégica en el aula de idiomas presenta aún dificultades relacionadas con el concepto y naturaleza de las estrategias, y con la metodología de instrucción.
Martín Leralta, Susana
doaj
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Deictic Expressions in the First SONAs of Rodrigo Duterte and Ferdinand Marcos Jr.
K@ta: A Biannual Publication on the Study of Language and LiteratureThis study assumes that former President Rodrigo Duterte and President Ferdinand Marcos Jr. used different types of deixis in their first State of the Nation Address (SONAs).
Ma. Sophia Pintado +4 more
doaj +1 more source
MENINGKATKAN KOMPETENSI STRATEGIS, PENALARAN ADAPTIF, DAN DISPOSISI PRODUKTIF SISWA SMA MELALUI CONCEPT-RICH INSTRUCTION [PDF]
, 2015 Kecakapan matematis siswa SMA, khususnya kompetensi strategis, penalaran adaptif, dan disposisi produktif masih rendah. Untuk itu diperlukan suatu pembelajaran yang dapat mengembangkan kemampuan-kemampuan tersebut, dalam hal ini Concept-Rich Instruction.
Rochyani, Sri Agung Ira
core
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source