Results 61 to 70 of about 29,088 (261)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

The Relationship between Metacognitive Strategies Awareness and Listening Comprehension of Non-Iranian Advanced Level Persian Language Learners [PDF]

زبان پژوهی
One of the challenges of second language learners is listening comprehension. In this context, Field (2008: 4) says that if we ask many language learners to determine the relative difficulty of the four language skills, many of them consider listening to
Seyed Akbar Jalili, Seyyed Mehdi Abtahi
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Changemaking: Building Strategic Competence

The Foundation Review, 2012
Keywords: Changemaking, community change, strategic competence, foundation reputation, staff-board alignmentIntroductionPhilanthropy has a long history of support for efforts to revitalize distressed communities and improve the lives of the children and families who live in them.
openaire   +3 more sources

Orientaciones para la inclusión de las estrategias en el programa habitual de ELE [PDF]

marcoELE. Revista de Didáctica Español Lengua Extranjera, 2008
Pese a haberse convertido en uno de los objetivos del currículo, el desarrollo de la competencia estratégica en el aula de idiomas presenta aún dificultades relacionadas con el concepto y naturaleza de las estrategias, y con la metodología de instrucción.
Martín Leralta, Susana
doaj  

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Deictic Expressions in the First SONAs of Rodrigo Duterte and Ferdinand Marcos Jr.

K@ta: A Biannual Publication on the Study of Language and Literature
This study assumes that former President Rodrigo Duterte and President Ferdinand Marcos Jr. used different types of deixis in their first State of the Nation Address (SONAs).
Ma. Sophia Pintado, Mark Jayce Cereño, Annalie Librea, Rechie Bejasa, Joemar Turno Minoza   +4 more
doaj   +1 more source