Results 31 to 40 of about 1,832,046 (296)
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
A Framework for Systemic Design
FORMakademisk, 2014 As designers move upstream from traditional product and service design to engage with challenges characterised by complexity, uniqueness, value conflict, and ambiguity over objectives, they have increasingly integrated systems approaches into their ...
Alex Ryan
doaj +1 more source
A strategic approach to transformational design [PDF]
, 1996 Designing parallel systems in a correct way is difficult. Transformational design of systems guarantees correctness by the correctness of the transformations, but is often tedious and complicated. We discuss different transformation strategies to guide the designer from the initial specification to different implementations, tailored to different ...
Jürgen Bohn 0002, Wil Janssen
openaire +1 more source
Sense and symbolic objects: Strategic sensemaking through design [PDF]
, 2012 This paper reports on an ongoing investigation into one aspect of the design thinking phenomenon, namely the use of designed artifacts — sketches, renderings, graphics, models and prototypes — as symbolic objects in strategy making and implementation. It
Stevens, John
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
A Map Of Uses Of Impact Evaluation Approaches
Journal of MultiDisciplinary EvaluationBackground: Not all evaluation practitioners are experts in the diversity of impact evaluation approaches. How can these approaches be made clear and accessible? How can practitioners be better able to choose the relevant one? A collaborative project was
Thomas Delahais +3 more
doaj +3 more sources
Challenges in Malaysian Design Industry
FORMakademiskThe Malaysian design industry follows a market-need-driven approach, where marketing-oriented managers guide designers to address anticipated high-demand markets.
Abu Ali +3 more
doaj +1 more source
How Design Plays Strategic Roles in Internet Service Innovation: Lessons from Korean Companies [PDF]
, 2008 In order to survive in the highly competitive internet business, companies have to provide differentiated services that can satisfy the rapidly changing users’ tastes and needs. Designers have been increasingly committed to achieving user satisfaction by
Chung, Kyung-won, Kim, Yu-Jin
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Urban Rail TransitThe unique physical characteristics and travel preferences of disabled individuals may lead to specific spatiotemporal characteristics of subway travel.
Jiandong Peng +4 more
doaj +1 more source